Details for Patent: 8,501,730

Which drugs does patent 8,501,730 protect, and when does it expire?

Patent 8,501,730 protects JYNARQUE and SAMSCA and is included in two NDAs.

This patent has fifty-six patent family members in fifteen countries.

Summary for Patent: 8,501,730

Title:	Process for preparing benzazepine compounds or salts thereof
Abstract:	This invention provides a process for preparing benzazepine compounds of the formula (1): wherein X1 is a halogen atom, R1 and R2 are a lower alkyl group, or salts thereof as well as intermediate benzoic acid compounds in high yield and high purity on industrial scale, which are useful as an intermediate for preparing a pharmaceutically active 2,3,4,5-tetrahydro-1H-1-benzazepine compound having vasopressin antagonistic activity.
Inventor(s):	Yasuhiro Torisawa, Kaoru Abe, Yasuaki Muguruma, Shigekazu Fujita, Hidenori Ogawa, Naoto Utsumi, Masahiro Miyake
Assignee:	Otsuka Pharmaceutical Co Ltd
Application Number:	US13/474,521
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 8,501,730
Patent Claim Types: see list of patent claims	Compound; Process;

Drugs Protected by US Patent 8,501,730

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Otsuka	JYNARQUE	tolvaptan	TABLET;ORAL	204441-001	Apr 23, 2018	AB2	RX	Yes	No	8,501,730			Y
Otsuka	JYNARQUE	tolvaptan	TABLET;ORAL	204441-002	Apr 23, 2018	AB2	RX	Yes	No	8,501,730			Y
Otsuka	JYNARQUE	tolvaptan	TABLET;ORAL	204441-003	Apr 23, 2018	AB	RX	Yes	Yes	8,501,730			Y

Foreign Priority and PCT Information for Patent: 8,501,730

Foriegn Application Priority Data
Foreign Country	Foreign Patent Number	Foreign Patent Date
Japan	2005-254744	Sep 02, 2005

International Family Members for US Patent 8,501,730

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Austria	E496895
Austria	E544744
China	101273017