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Generated: August 25, 2019

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Details for Patent: 8,461,137

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Which drugs does patent 8,461,137 protect, and when does it expire?

Patent 8,461,137 protects APADAZ and is included in one NDA.

This patent has thirty-two patent family members in nineteen countries.

Summary for Patent: 8,461,137
Title:Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof
Abstract: The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs/compositions of hydrocodone, including benzoates and heteroaryl carboxylic acids, which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology.
Inventor(s): Mickle; Travis (Coralville, IA), Guenther; Sven (Coralville, IA), Mickle; Christal (Coralville, IA), Chi; Guochen (North Liberty, IA), Kanski; Jaroslaw (Blacksburg, VA), Martin; Andrea K. (Fincastle, VA), Bera; Bindu (Blacksburg, VA)
Assignee: KemPharm, Inc. (North Liberty, IA)
Application Number:12/828,381
Patent Claim Types:
see list of patent claims
Composition; Formulation; Compound; Dosage form;

Drugs Protected by US Patent 8,461,137

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Kvk Tech Inc APADAZ acetaminophen; benzhydrocodone hydrochloride TABLET;ORAL 208653-002 Jan 4, 2019 RX Yes No   Try a Free Trial   Try a Free Trial Y Y   Try a Free Trial
Kvk Tech Inc APADAZ acetaminophen; benzhydrocodone hydrochloride TABLET;ORAL 208653-001 Feb 23, 2018 RX Yes No   Try a Free Trial   Try a Free Trial Y Y   Try a Free Trial
Kvk Tech Inc APADAZ acetaminophen; benzhydrocodone hydrochloride TABLET;ORAL 208653-003 Jan 4, 2019 RX Yes No   Try a Free Trial   Try a Free Trial Y Y   Try a Free Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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