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Serving hundreds of leading biopharmaceutical companies globally:

Healthtrust
Mallinckrodt
Argus Health
McKesson
Deloitte
US Army
Cipla
Federal Trade Commission
Colorcon

Generated: June 23, 2018

DrugPatentWatch Database Preview

Details for Patent: 8,424,518

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Summary for Patent: 8,424,518
Title:Dry powder inhaler and system for drug delivery
Abstract: A breath-powered, dry powder inhaler, a cartridge, and a pulmonary drug delivery system are provided. The dry powder inhaler can be provided with or without a unit dose cartridge for using with the inhaler. The inhaler and/or cartridge can be provided with a drug delivery formulation comprising, for example, a diketopiperazine and an active ingredient, including, peptides and proteins such as insulin and glucagon-like peptide 1 for the treatment of diabetes and/or obesity. The dry powder inhaler is compact; can be provided in various shapes and sizes, colors, and comprises a housing, a mouthpiece, a cartridge placement area, and a mechanism for opening and closing the medicament cartridge. The device is easy to manufacture, provides a pre-metered single unit dose, it is relatively easy to use, and can be reusable or disposable.
Inventor(s): Smutney; Chad C. (Watertown, CT), Kinsey; P. Spencer (Sandy Hook, CT), Sahi; Carl R. (Coventry, CT), Adamo; Benoit (Mount Kisco, NY), Polidoro; John M. (Conventry, CT), McLean; Scott (Waterbury, CT), Overfield; Dennis (Fairfield, CT), Bryant; Anthony (Stratford, CT)
Assignee: Mannkind Corporation (Valencia, CA)
Application Number:12/484,137
Patent Claim Types:
see list of patent claims
Delivery; Composition;

Drugs Protected by US Patent 8,424,518

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Mannkind AFREZZA insulin recombinant human POWDER;INHALATION 022472-001 Jun 27, 2014 RX Yes No ➤ Sign Up ➤ Sign Up Y ➤ Sign Up
Mannkind AFREZZA insulin recombinant human POWDER;INHALATION 022472-002 Jun 27, 2014 RX Yes Yes ➤ Sign Up ➤ Sign Up Y ➤ Sign Up
Mannkind AFREZZA insulin recombinant human POWDER;INHALATION 022472-003 Apr 17, 2015 RX Yes No ➤ Sign Up ➤ Sign Up Y ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 8,424,518

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
8,377,869 Method of preventing adverse effects by GLP-1 ➤ Sign Up
9,446,133 Dry powder inhaler and system for drug delivery ➤ Sign Up
9,446,001 Increasing drug affinity for crystalline microparticle surfaces ➤ Sign Up
9,511,198 Dry powder inhaler and system for drug delivery ➤ Sign Up
Patent No. Title Estimated Patent Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Express Scripts
Mallinckrodt
Daiichi Sankyo
Cantor Fitzgerald
Dow
Chubb
Medtronic
Johnson and Johnson
AstraZeneca

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