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Last Updated: September 17, 2021

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Details for Patent: 8,361,977


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Which drugs does patent 8,361,977 protect, and when does it expire?

Patent 8,361,977 protects SPINRAZA and is included in one NDA.

This patent has thirty patent family members in twelve countries.

Summary for Patent: 8,361,977
Title:Compositions and methods for modulation of SMN2 splicing
Abstract: Disclosed herein are compounds, compositions and methods for modulating splicing of SMN2 mRNA in a cell, tissue or animal. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders, including spinal muscular atrophy.
Inventor(s): Baker; Brenda F. (Carlsbad, CA), Krainer; Adrian R. (Huntington Station, NY), Hua; Yimin (Jericho, NY)
Assignee: Isis Pharmaceuticals, Inc. (Carlsbad, CA)
Application Number:11/993,609
Patent Claim Types:
see list of patent claims
Compound; Composition;

Drugs Protected by US Patent 8,361,977

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Biogen Idec SPINRAZA nusinersen sodium SOLUTION;INTRATHECAL 209531-001 Dec 23, 2016 RX Yes Yes ⤷  Try it Free ⤷  Try it Free Y Y ⤷  Try it Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 8,361,977

PCT Information
PCT FiledJune 23, 2006PCT Application Number:PCT/US2006/024469
PCT Publication Date:January 04, 2007PCT Publication Number: WO2007/002390

International Family Members for US Patent 8,361,977

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Cyprus 1116663 ⤷  Try it Free
Cyprus 1121134 ⤷  Try it Free
Denmark 1910395 ⤷  Try it Free
Denmark 2548560 ⤷  Try it Free
Denmark 3308788 ⤷  Try it Free
European Patent Office 1910395 ⤷  Try it Free CA 2017 00054 Denmark ⤷  Try it Free
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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Serving leading biopharmaceutical companies globally:

Medtronic
Moodys
McKinsey
McKesson
Merck
Johnson and Johnson

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