Last Updated: June 25, 2026

Details for Patent: 8,278,292


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Which drugs does patent 8,278,292 protect, and when does it expire?

Patent 8,278,292 protects PICATO and is included in one NDA.

This patent has thirty-three patent family members in twenty-one countries.

Summary for Patent: 8,278,292
Title:Therapeutic compositions
Abstract:Ingenol angelate is a potent anticancer agent, and can be stabilized by dissolving it in an aprotic solvent in the presence of an acidic buffer.
Inventor(s):Marc Barry Brown, Michael Edward Donald Crowthers, Tahir Nazir
Assignee: AF 30 APRIL 2003 AS , Leo Laboratories Ltd
Application Number:US12/097,258
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 8,278,292
Patent Claim Types:
see list of patent claims
Formulation; Compound;

Drugs Protected by US Patent 8,278,292

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Leo Labs PICATO ingenol mebutate GEL;TOPICAL 202833-001 Jan 23, 2012 DISCN Yes No ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
Leo Labs PICATO ingenol mebutate GEL;TOPICAL 202833-002 Jan 23, 2012 DISCN Yes No ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 8,278,292

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom0525680.5Dec 16, 2005
PCT Information
PCT FiledDecember 18, 2006PCT Application Number:PCT/GB2006/004739
PCT Publication Date:June 21, 2007PCT Publication Number: WO2007/068963

International Family Members for US Patent 8,278,292

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 1988877 ⤷  Start Trial C300682 Netherlands ⤷  Start Trial
European Patent Office 1988877 ⤷  Start Trial PA2014030 Lithuania ⤷  Start Trial
European Patent Office 1988877 ⤷  Start Trial CA 2014 00042 Denmark ⤷  Start Trial
European Patent Office 1988877 ⤷  Start Trial C20140025 00111 Estonia ⤷  Start Trial
European Patent Office 1988877 ⤷  Start Trial C01988877/01 Switzerland ⤷  Start Trial
European Patent Office 1988877 ⤷  Start Trial 14C0058 France ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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