Last Updated: September 24, 2026

Details for Patent: 8,247,415


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Which drugs does patent 8,247,415 protect, and when does it expire?

Patent 8,247,415 protects GEMTESA and is included in one NDA.

This patent has fifty-nine patent family members in forty-four countries.

Summary for Patent: 8,247,415
Title:Hydroxymethyl pyrrolidines as β3 adrenergic receptor agonists
Abstract:The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
Inventor(s):Richard Berger, Lehua Chang, Scott D. Edmondson, Stephen D. Goble, Sookhee Nicole Ha, Nam Fung Kar, Ihor E. Kopka, Bing Li, Gregori J. Morriello, Chris R. Moyes, Dong-ming Shen, Liping Wang, Cheng Zhu
Assignee: Merck Sharp and Dohme LLC
Application Number:US12/417,239
Patent Claim Types:
see list of patent claims
Use; Composition;

Drugs Protected by US Patent 8,247,415

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Sumitomo Pharma Am GEMTESA vibegron TABLET;ORAL 213006-001 Dec 23, 2020 RX Yes Yes ⤷  Start Trial ⤷  Start Trial Y Y TREATMENT OF OVERACTIVE BLADDER (OAB) WITH SYMPTOMS OF URGE URINARY INCONTINENCE, URGENCY, AND URINARY FREQUENCY IN ADULT MALES ON PHARMACOLOGICAL THERAPY FOR BENIGN PROSTATIC HYPERPLASIA (BPH) ⤷  Start Trial
Sumitomo Pharma Am GEMTESA vibegron TABLET;ORAL 213006-001 Dec 23, 2020 RX Yes Yes ⤷  Start Trial ⤷  Start Trial Y Y TREATMENT OF OVERACTIVE BLADDER (OAB) WITH SYMPTOMS OF URGE URINARY INCONTINENCE, URGENCY, AND URINARY FREQUENCY ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 8,247,415

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 2276756 ⤷  Start Trial 301305 Netherlands ⤷  Start Trial
European Patent Office 2276756 ⤷  Start Trial CA 2024 00054 Denmark ⤷  Start Trial
European Patent Office 2276756 ⤷  Start Trial LUC00366 Luxembourg ⤷  Start Trial
European Patent Office 2276756 ⤷  Start Trial CR 2024 00054 Denmark ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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