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Last Updated: May 8, 2024

Details for Patent: 8,236,766


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Which drugs does patent 8,236,766 protect, and when does it expire?

Patent 8,236,766 protects KORSUVA and is included in one NDA.

This patent has forty-nine patent family members in twenty-five countries.

Summary for Patent: 8,236,766
Title:Uses of synthetic peptide amides
Abstract: The invention relates to synthetic peptide amides that are ligands of the kappa opioid receptor and particularly to agonists of the kappa opioid receptor that exhibit low P.sub.450 CYP inhibition and low penetration into the brain. The synthetic peptide amides of the invention conform to the structure: ##STR00001## wherein Xaa is a D-amino acid and G is selected from the following three groups: ##STR00002## The compounds are useful in the prophylaxis and treatment of pain, pruritus and inflammation associated with a variety of diseases and conditions.
Inventor(s): Schteingart; Claudio D. (San Diego, CA), Menzaghi; Frederique (Rye, NY), Jiang; Guangcheng (San Diego, CA), Alexander; Roberta Vezza (San Diego, CA), Sueiras-Diaz; Javier (La Jolla, CA), Spencer; Robert H. (New Hope, PA), Chalmers; Derek T. (Riverside, CT), Luo; Zhiyong (New City, NY)
Assignee: Cara Therapeutics, Inc. (Shelton, CT)
Application Number:12/480,059
Patent Claim Types:
see list of patent claims
Use; Composition;

Drugs Protected by US Patent 8,236,766

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Cara Therap KORSUVA difelikefalin acetate SOLUTION;INTRAVENOUS 214916-001 Aug 23, 2021 RX Yes Yes ⤷  Try a Trial ⤷  Try a Trial TREATMENT OF MODERATE-TO-SEVERE PRURITUS ASSOCIATED WITH CHRONIC KIDNEY DISEASE (CKD-AP) IN ADULTS UNDERGOING HEMODIALYSIS (HD) ⤷  Try a Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 8,236,766

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2007317817 ⤷  Try a Trial
Australia 2007319831 ⤷  Try a Trial
Brazil PI0718651 ⤷  Try a Trial
Canada 2667155 ⤷  Try a Trial
Canada 2667460 ⤷  Try a Trial
Canada 2898514 ⤷  Try a Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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