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Last Updated: October 27, 2020

DrugPatentWatch Database Preview

Details for Patent: 8,222,244

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Which drugs does patent 8,222,244 protect, and when does it expire?

Patent 8,222,244 protects RYDAPT and is included in one NDA.

This patent has thirty-four patent family members in twenty-four countries.

Summary for Patent: 8,222,244
Title:Staurosporine derivatives as inhibitors of FLT3 receptor tyrosine kinase activity
Abstract: The present invention relates to the use of staurosporines derivatives for the preparation of a drug for the treatment of diseases involving deregulated FLT3 receptor tyrosine kinase activity, especially for the curative and/or prophylactic treatment of leukemias and myelodysplastic syndromes, and to a method of treating diseases involving deregulated FLT3 receptor tyrosine kinase activity.
Inventor(s): Griffin; James D (Brookline, MA), Manley; Paul W (Arlesheim, CH)
Assignee: Novartis AG (Basel, CH) Dana-Farber Cancer Institute Inc. (Boston, MA)
Application Number:13/109,511
Patent Claim Types:
see list of patent claims
Use; Delivery;

Drugs Protected by US Patent 8,222,244

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Novartis RYDAPT midostaurin CAPSULE;ORAL 207997-001 Apr 28, 2017 RX Yes Yes   Start Trial   Start Trial TREATMENT OF ADULT PATIENTS WITH NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA (AML) WHO ARE FLT3 MUTATION-POSITIVE, IN COMBINATION WITH STANDARD CYTARABINE AND DAUNORUBICIN INDUCTION AND CYTARABINE CONSOLIDATION CHEMOTHERAPY   Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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Serving leading biopharmaceutical companies globally:

Johnson and Johnson
McKesson
Merck
Mallinckrodt
Medtronic
Moodys

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