Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving hundreds of leading biopharmaceutical companies globally:

Colorcon
Medtronic
Chubb
Teva
Express Scripts
McKinsey
Boehringer Ingelheim
Julphar
Dow

Generated: April 23, 2018

DrugPatentWatch Database Preview

Details for Patent: 8,182,835

« Back to Dashboard

Which drugs does patent 8,182,835 protect, and when does it expire?

Patent 8,182,835 protects EXPAREL and is included in one NDA.

This patent has twenty patent family members in fifteen countries.
Summary for Patent: 8,182,835
Title:Sustained-release liposomal anesthetic compositions
Abstract: The invention provides a method for obtaining local anesthetics encapsulated in liposomes, such as multivesicular liposomes, with high encapsulation efficiency and slow release in vivo. When the encapsulated anesthetic is administered as a single intracutaneous dose, the duration of anesthesia and half-life of the drug at the local injection site is increased as compared to injection of unencapsulated anesthetic. The maximum tolerated dose of the encapsulated anesthetic is also markedly increased in the liposomal formulation over injection of unencapsulated anesthetic. These results show that the liposomal formulation of local anesthetic is useful for sustained local infiltration and nerve block anesthesia.
Inventor(s): Kim; Sinil (Solana Beach, CA), Kim; Taehee (Los Angeles, CA), Murdande; Sharad (Groton, CT)
Assignee: Pacira Pharmaceuticals, Inc. (San Diego, CA)
Application Number:11/097,756
Patent Claim Types:
see list of patent claims
Formulation; Compound; Dosage form; Process; Composition; Use;

Drugs Protected by US Patent 8,182,835

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Pacira Pharms Inc EXPAREL bupivacaine INJECTABLE, LIPOSOMAL;INJECTION 022496-001 Oct 28, 2011 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial Y SINGLE DOSE ADMINISTRATION INTO THE SURGICAL SITE TO PRODUCE POSTSURGICAL ANALGESIA ➤ Try a Free Trial
Pacira Pharms Inc EXPAREL bupivacaine INJECTABLE, LIPOSOMAL;INJECTION 022496-002 Oct 28, 2011 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial Y SINGLE DOSE ADMINISTRATION INTO THE SURGICAL SITE TO PRODUCE POSTSURGICAL ANALGESIA ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

This preview shows a limited data set. Subscribe for full access, or try a Free Trial

Non-Orange Book US Patents Family Members for Patent 8,182,835

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
9,192,575 Sustained-release liposomal anesthetic compositions ➤ Try a Free Trial
9,205,052 Sustained-release liposomal anesthetic compositions ➤ Try a Free Trial
6,045,824 Sustained-release liposomal anesthetic compositions ➤ Try a Free Trial
8,834,921 Sustained-release liposomal anesthetic compositions ➤ Try a Free Trial
Patent No. Title Estimated Patent Expiration

This preview shows a limited data set. Subscribe for full access, or try a Free Trial

International Patents Family Members for US Patent 8,182,835

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 463238 ➤ Try a Free Trial
Austria 535232 ➤ Try a Free Trial
Australia 735588 ➤ Try a Free Trial
Australia 9494298 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

This preview shows a limited data set. Subscribe for full access, or try a Free Trial

For more information try a trial or see the plans and pricing

Serving hundreds of leading biopharmaceutical companies globally:

Citi
McKesson
QuintilesIMS
US Army
Mallinckrodt
Teva
Express Scripts
Queensland Health
Merck

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.