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Last Updated: September 28, 2021

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Details for Patent: 8,182,835


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Summary for Patent: 8,182,835
Title:Sustained-release liposomal anesthetic compositions
Abstract: The invention provides a method for obtaining local anesthetics encapsulated in liposomes, such as multivesicular liposomes, with high encapsulation efficiency and slow release in vivo. When the encapsulated anesthetic is administered as a single intracutaneous dose, the duration of anesthesia and half-life of the drug at the local injection site is increased as compared to injection of unencapsulated anesthetic. The maximum tolerated dose of the encapsulated anesthetic is also markedly increased in the liposomal formulation over injection of unencapsulated anesthetic. These results show that the liposomal formulation of local anesthetic is useful for sustained local infiltration and nerve block anesthesia.
Inventor(s): Kim; Sinil (Solana Beach, CA), Kim; Taehee (Los Angeles, CA), Murdande; Sharad (Groton, CT)
Assignee: Pacira Pharmaceuticals, Inc. (San Diego, CA)
Application Number:11/097,756
Patent Claim Types:
see list of patent claims
Formulation; Compound; Dosage form; Process; Composition; Use;

Drugs Protected by US Patent 8,182,835

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 8,182,835

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 463238 ⤷  Free Forever Trial
Austria 535232 ⤷  Free Forever Trial
Australia 735588 ⤷  Free Forever Trial
Australia 9494298 ⤷  Free Forever Trial
Canada 2304096 ⤷  Free Forever Trial
Cyprus 1110135 ⤷  Free Forever Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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