Details for Patent: 8,178,693
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Which drugs does patent 8,178,693 protect, and when does it expire?
Patent 8,178,693 protects KOSELUGO and is included in one NDA.
This patent has one hundred and twenty-three patent family members in thirty-four countries.
Summary for Patent: 8,178,693
| Title: | N3 alkylated benzimidazole derivatives as MEK inhibitors |
| Abstract: | Disclosed are compounds of the Formula ##STR00001## and pharmaceutically acceptable salts and prodrugs thereof, wherein A, R.sup.1, R.sup.2, R.sup.7, R.sup.8, and R.sup.9 are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals. Also disclosed is a method of using such compounds in the treatment of hyperproliferative diseases in mammals, and pharmaceutical compositions containing such compounds. |
| Inventor(s): | Wallace; Eli M. (Boulder, CO), Lyssikatos; Joseph P. (Piedmont, CA), Marlow; Allison L. (Boulder, CO), Hurley; T. Brian (Boulder, CO) |
| Assignee: | Array Biopharma Inc. (Boulder, CO) |
| Application Number: | 12/824,559 |
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Patent Claim Types: see list of patent claims | Composition; Compound; |
Drugs Protected by US Patent 8,178,693
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Astrazeneca | KOSELUGO | selumetinib sulfate | CAPSULE;ORAL | 213756-001 | Apr 10, 2020 | RX | Yes | No | ⤷ Try a Trial | ⤷ Try a Trial | Y | Y | ⤷ Try a Trial | |||
| Astrazeneca | KOSELUGO | selumetinib sulfate | CAPSULE;ORAL | 213756-002 | Apr 10, 2020 | RX | Yes | Yes | ⤷ Try a Trial | ⤷ Try a Trial | Y | Y | ⤷ Try a Trial | |||
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 8,178,693
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| Argentina | 038971 | ⤷ Try a Trial | |||
| Argentina | 045738 | ⤷ Try a Trial | |||
| Argentina | 090143 | ⤷ Try a Trial | |||
| Argentina | 090144 | ⤷ Try a Trial | |||
| Austria | 449605 | ⤷ Try a Trial | |||
| Australia | 2003218157 | ⤷ Try a Trial | |||
| Australia | 2004270166 | ⤷ Try a Trial | |||
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
