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Serving hundreds of leading biopharmaceutical companies globally:

Merck
Baxter
Farmers Insurance
Moodys
Johnson and Johnson
Healthtrust
Deloitte
Accenture
Chubb

Generated: June 20, 2018

DrugPatentWatch Database Preview

Details for Patent: 8,138,195

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Which drugs does patent 8,138,195 protect, and when does it expire?

Patent 8,138,195 protects ZYDELIG and is included in one NDA.

This patent has fifty-three patent family members in twenty-nine countries.
Summary for Patent: 8,138,195
Title:Inhibitors of human phosphatidylinositol 3-kinase delta
Abstract: Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (PI3K.delta.) activity, and methods of treating diseases, such as disorders of immunity and inflammation, in which PI3K.delta. plays a role in leukocyte function are disclosed. Preferably, the methods employ active agents that selectively inhibit PI3K.delta., while not significantly inhibiting activity of other PI3K isoforms. Compounds are provided that inhibit PI3K.delta. activity, including compounds that selectively inhibit PI3K.delta. activity. Methods of using PI3K.delta. inhibitory compounds to inhibit cancer cell growth or proliferation are also provided. Accordingly, the invention provides methods of using PI3K.delta. inhibitory compounds to inhibit PI3K.delta.-mediated processes in vitro and in vivo.
Inventor(s): Sadhu; Chanchal (Bothell, WA), Dick; Kenneth O. (Bothell, WA), Treiberg; Jennifer (Bothell, WA), Sowell; C. Gregory (Mukilteo, WA), Kesicki; Edward A. (Bothell, WA), Oliver; Amy (Bothell, WA)
Assignee: ICOS Corporation (Bothell, WA)
Application Number:11/110,204
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

Drugs Protected by US Patent 8,138,195

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Gilead Sciences Inc ZYDELIG idelalisib TABLET;ORAL 205858-001 Jul 23, 2014 RX Yes No ➤ Try a Free Trial ➤ Try a Free Trial Y Y FOR THE TREATMENT OF PATIENTS WITH RELAPSED CHRONIC LYMPHOCYTIC LEUKEMIA ➤ Try a Free Trial
Gilead Sciences Inc ZYDELIG idelalisib TABLET;ORAL 205858-002 Jul 23, 2014 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial Y Y FOR THE TREATMENT OF PATIENTS WITH RELAPSED CHRONIC LYMPHOCYTIC LEUKEMIA ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 8,138,195

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
6,949,535 Inhibitors of human phosphatidyl-inositol 3-kinase delta ➤ Try a Free Trial
8,623,881 Inhibitors of human phosphatidylinositol 3-kinase delta ➤ Try a Free Trial
8,637,533 Inhibitors of human phosphatidylinositol 3-kinase delta ➤ Try a Free Trial
6,518,277 Inhibitors of human phosphatidylinositol 3-kinase delta ➤ Try a Free Trial
Patent No. Title Estimated Patent Expiration

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International Family Members for US Patent 8,138,195

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 493131 ➤ Try a Free Trial
Austria 502941 ➤ Try a Free Trial
Australia 2001255667 ➤ Try a Free Trial
Australia 2002323426 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

US Army
Chubb
Teva
Accenture
Deloitte
Dow
Boehringer Ingelheim
Chinese Patent Office
AstraZeneca

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