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Serving leading biopharmaceutical companies globally:

Novartis
Healthtrust
Harvard Business School
QuintilesIMS
Chubb
Queensland Health
Fuji
McKesson
Cipla
Julphar

Generated: February 23, 2018

DrugPatentWatch Database Preview

Details for Patent: 8,138,195

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Which drugs does patent 8,138,195 protect, and when does it expire?

Patent 8,138,195 protects ZYDELIG and is included in one NDA.

This patent has fifty-three patent family members in twenty-nine countries.
Summary for Patent: 8,138,195
Title:Inhibitors of human phosphatidylinositol 3-kinase delta
Abstract: Methods of inhibiting phosphatidylinositol 3-kinase delta isoform (PI3K.delta.) activity, and methods of treating diseases, such as disorders of immunity and inflammation, in which PI3K.delta. plays a role in leukocyte function are disclosed. Preferably, the methods employ active agents that selectively inhibit PI3K.delta., while not significantly inhibiting activity of other PI3K isoforms. Compounds are provided that inhibit PI3K.delta. activity, including compounds that selectively inhibit PI3K.delta. activity. Methods of using PI3K.delta. inhibitory compounds to inhibit cancer cell growth or proliferation are also provided. Accordingly, the invention provides methods of using PI3K.delta. inhibitory compounds to inhibit PI3K.delta.-mediated processes in vitro and in vivo.
Inventor(s): Sadhu; Chanchal (Bothell, WA), Dick; Kenneth O. (Bothell, WA), Treiberg; Jennifer (Bothell, WA), Sowell; C. Gregory (Mukilteo, WA), Kesicki; Edward A. (Bothell, WA), Oliver; Amy (Bothell, WA)
Assignee: ICOS Corporation (Bothell, WA)
Application Number:11/110,204
Patent Claim Types:
see list of patent claims
Compound; Use; Composition;

Drugs Protected by US Patent 8,138,195

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Gilead Sciences Inc ZYDELIG idelalisib TABLET;ORAL 205858-001 Jul 23, 2014 RX Yes No ➤ Sign Up ➤ Sign Up Y Y FOR THE TREATMENT OF PATIENTS WITH RELAPSED CHRONIC LYMPHOCYTIC LEUKEMIA ➤ Sign Up
Gilead Sciences Inc ZYDELIG idelalisib TABLET;ORAL 205858-002 Jul 23, 2014 RX Yes Yes ➤ Sign Up ➤ Sign Up Y Y FOR THE TREATMENT OF PATIENTS WITH RELAPSED CHRONIC LYMPHOCYTIC LEUKEMIA ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 8,138,195

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
6,518,277 Inhibitors of human phosphatidylinositol 3-kinase delta ➤ Sign Up
6,949,535 Inhibitors of human phosphatidyl-inositol 3-kinase delta ➤ Sign Up
9,487,772 Inhibitors of human phosphatidylinositol 3-kinase delta ➤ Sign Up
8,492,389 Inhibitors of human phosphatidylinositol 3-kinase delta ➤ Sign Up
8,637,533 Inhibitors of human phosphatidylinositol 3-kinase delta ➤ Sign Up
8,653,077 Inhibitors of human phosphatidylinositol 3-kinase delta ➤ Sign Up
8,623,881 Inhibitors of human phosphatidylinositol 3-kinase delta ➤ Sign Up
6,667,300 Inhibitors of human phosphatidylinositol 3-kinase delta ➤ Sign Up
6,800,620 Inhibitors of human phosphatidylinositol 3-kinase delta ➤ Sign Up
Patent No. Title Estimated Patent Expiration

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International Patents Family Members for US Patent 8,138,195

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Denmark 1278748 ➤ Sign Up
China 1440408 ➤ Sign Up
China 1606444 ➤ Sign Up
Cyprus 1116299 ➤ Sign Up
Cyprus 1117672 ➤ Sign Up
Germany 60144277 ➤ Sign Up
Denmark 1438052 ➤ Sign Up
Denmark 1939203 ➤ Sign Up
Denmark 2223922 ➤ Sign Up
Austria 493131 ➤ Sign Up
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Teva
Fuji
Merck
Fish and Richardson
Dow
Harvard Business School
Daiichi Sankyo
McKinsey
Cerilliant

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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