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Serving leading biopharmaceutical companies globally:

Farmers Insurance
Covington
Medtronic
Colorcon
AstraZeneca
Accenture
Argus Health
Express Scripts
Dow
US Department of Justice

Generated: January 17, 2018

DrugPatentWatch Database Preview

Details for Patent: 8,133,890

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Which drugs does patent 8,133,890 protect, and when does it expire?

Patent 8,133,890 protects COMBIGAN and is included in one NDA.

This patent has twenty-two patent family members in nineteen countries.
Summary for Patent: 8,133,890
Title:Combination of brimonidine and timolol for topical ophthalmic use
Abstract: Disclosed are pharmaceutical compositions comprising brimondine and timolol for topical ophthalmic delivery and a method of treatment comprising administering said composition when indicated for glaucoma and associated conditions such as elevated intraocular pressure in the eyes of humans.
Inventor(s): Chang; Chin-Ming (Tustin, CA), Beck; Gary J. (Fullerton, CA), Pratt; Cynthia C. (Mission Viejo, CA), Batoosingh; Amy L. (Mission Viejo, CA)
Assignee: Allergan, Inc. (Irvine, CA)
Application Number:11/946,828
Patent Claim Types:
see list of patent claims
Use; Composition;

Drugs Protected by US Patent 8,133,890

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Allergan COMBIGAN brimonidine tartrate; timolol maleate SOLUTION/DROPS;OPHTHALMIC 021398-001 Oct 30, 2007 RX Yes Yes ➤ Subscribe ➤ Subscribe REDUCTION OF ELEVATED INTRAOCULAR PRESSURE IN PATIENTS WITH GLAUCOMA OR OCULAR HYPERTENSION ➤ Subscribe
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 8,133,890

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
8,354,409 Combination of brimonidine and timolol for topical ophthalmic use ➤ Subscribe
7,030,149 Combination of brimonidine timolol for topical ophthalmic use ➤ Subscribe
9,770,453 Combination of brimonidine and timolol for topical ophthalmic use ➤ Subscribe
7,320,976 Combination of brimonidine and timolol for topical ophthalmic use ➤ Subscribe
8,748,425 Combination of brimonidine and timolol for topical ophthalmic use ➤ Subscribe
7,642,258 Combination of brimonidine and timolol for topical ophthalmic use ➤ Subscribe
7,323,463 Combination of brimonidine and timolol for topical ophthalmic use ➤ Subscribe
9,474,751 Combination of brimonidine and timolol for topical ophthalmic use ➤ Subscribe
Patent No. Title Estimated Patent Expiration

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International Patents Family Members for US Patent 8,133,890

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2003228480 ➤ Subscribe
Brazil 0302584 ➤ Subscribe
Canada 2440764 ➤ Subscribe
China 100558364 ➤ Subscribe
China 101664414 ➤ Subscribe
China 1516588 ➤ Subscribe
Cyprus 1114048 ➤ Subscribe
Denmark 1496912 ➤ Subscribe
Ecuador SP034742 ➤ Subscribe
European Patent Office 1496912 ➤ Subscribe
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving leading biopharmaceutical companies globally:

Julphar
Harvard Business School
Queensland Health
Boehringer Ingelheim
Moodys
Covington
Healthtrust
Mallinckrodt
Chubb

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