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Serving leading biopharmaceutical companies globally:

McKinsey
Farmers Insurance
Moodys
Julphar
Accenture
Dow
US Army
Federal Trade Commission
Healthtrust
Fish and Richardson

Generated: February 25, 2018

DrugPatentWatch Database Preview

Details for Patent: 8,129,342

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Summary for Patent: 8,129,342
Title:High purity lipopeptides
Abstract: The invention discloses highly purified daptomycin and to pharmaceutical compositions comprising this compound. The invention discloses a method of purifying daptomycin comprising the sequential steps of anion exchange chromatography, hydrophobic interaction chromatography and anion exchange chromatography. The invention also discloses a method of purifying daptomycin by modified buffer enhanced anion exchange chromatography. The invention also discloses an improved method for producing daptomycin by fermentation of Streptomyces roseosporus. The invention also discloses high pressure liquid chromatography methods for analysis of daptomycin purity. The invention also discloses lipopeptide micelles and methods of making the micelles. The invention also discloses methods of using lipopeptide micelles for purifying lipopeptide antibiotics, such as daptomycin. The invention also discloses using lipopeptide micelles therapeutically.
Inventor(s): Kelleher; Thomas J. (Thousand Oaks, CA), Lai; Jan-Ji (Westborough, MA), DeCourcey; Joseph P. (Boston, MA), Lynch; Paul D. (Arlington, MA), Zenoni; Maurizio (Ferentino Frosinone, IT), Tagliani; Auro R. (Pavia, IT)
Assignee: Cubist Pharmaceuticals, Inc. (Lexington, MA)
Application Number:12/888,233
Patent Claim Types:
see list of patent claims
Composition; Process; Use; Formulation;

Drugs Protected by US Patent 8,129,342

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Patents Family Members for US Patent 8,129,342

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Serving hundreds of leading biopharmaceutical companies globally:

McKesson
Dow
Julphar
Queensland Health
AstraZeneca
Covington
Express Scripts
Harvard Business School
Fuji

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