Last Updated: August 11, 2026

Details for Patent: 8,114,874


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Which drugs does patent 8,114,874 protect, and when does it expire?

Patent 8,114,874 protects ICLUSIG and is included in one NDA.

This patent has seventy-two patent family members in twenty-one countries.

Summary for Patent: 8,114,874
Title:Substituted acetylenic imidazo[1,2-B]pyridazine compounds as kinase inhibitors
Abstract:This invention relates to compounds of the general formula:
Inventor(s):Dong Zou, Wei-Sheng Huang, R. Mathew Thomas, Jan Antionette C. Romero, Jiwei Qi, Yihan Wang, Xiaotian Zhu, William C. Shakespeare, Rajeswari Sundaramoorthi, Chester A. Metcalf, III, David C. Dalgarno, Tomi K. Sawyer
Assignee: Takeda Pharmaceuticals USA Inc
Application Number:US11/644,849
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 8,114,874
Patent Claim Types:
see list of patent claims
Composition; Compound;
Patent landscape, scope, and claims:

error: insufficient information

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Drugs Protected by US Patent 8,114,874

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Takeda Pharms Usa ICLUSIG ponatinib hydrochloride TABLET;ORAL 203469-004 Dec 18, 2020 RX Yes Yes ⤷  Start Trial ⤷  Start Trial Y Y ⤷  Start Trial
Takeda Pharms Usa ICLUSIG ponatinib hydrochloride TABLET;ORAL 203469-001 Dec 14, 2012 RX Yes No ⤷  Start Trial ⤷  Start Trial Y Y ⤷  Start Trial
Takeda Pharms Usa ICLUSIG ponatinib hydrochloride TABLET;ORAL 203469-003 Apr 23, 2015 RX Yes No ⤷  Start Trial ⤷  Start Trial Y Y ⤷  Start Trial
Takeda Pharms Usa ICLUSIG ponatinib hydrochloride TABLET;ORAL 203469-002 Dec 14, 2012 RX Yes No ⤷  Start Trial ⤷  Start Trial Y Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 8,114,874

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 1973545 ⤷  Start Trial C300631 Netherlands ⤷  Start Trial
European Patent Office 1973545 ⤷  Start Trial CA 2013 00066 Denmark ⤷  Start Trial
European Patent Office 1973545 ⤷  Start Trial PA2013027 Lithuania ⤷  Start Trial
European Patent Office 1973545 ⤷  Start Trial 92327 Luxembourg ⤷  Start Trial
European Patent Office 1973545 ⤷  Start Trial 13C0069 France ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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