Details for Patent: 8,074,644
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Summary for Patent: 8,074,644
Title: | Method of forming an aerosol for inhalation delivery |
Abstract: | The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. In a method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug at a rate greater than 1000.degree. C./s, thereby forming an vapor; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug to form a vapor, wherein the coated composition is in the form of a film less than 10.mu. thick; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. In another method aspect of the present invention, a method of forming an aerosol for use in inhalation therapy is provided. The method involves the following steps: (a) heating a substrate coated with a composition comprising a drug to form a vapor in less than 100 milliseconds, wherein the vapor has a mass greater than 0.1 mg; and, (b) allowing the vapor to cool, thereby forming an aerosol, which is used in inhalation therapy. |
Inventor(s): | Hale; Ron L. (Sandia Park, NM), Hodges; Craig C. (Walnut Creek, CA), Lloyd; Peter M. (Walnut Creek, CA), Mufson; Daniel (Napa, CA), Rogers; Daniel D. (Oakland, CA), Song; Soonho (Hillsborough, CA), Wensley; Martin J. (Los Gatos, CA), Myers; Daniel J. (Mountain View, CA), McKinney; Jeffrey A. (Lafayette, CA), Quintana; Reynaldo J. (Redwood City, CA), Rabinowitz; Joshua D. (Princeton, NJ) |
Assignee: | Alexza Pharmaceuticals, Inc. (Mountain View, CA) |
Application Number: | 12/471,070 |
Patent Claim Types: see list of patent claims | Use; Composition; |
Drugs Protected by US Patent 8,074,644
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International Family Members for US Patent 8,074,644
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
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Austria | 365548 | ⤷ Try a Trial | |||
Austria | 401063 | ⤷ Try a Trial | |||
Austria | 401064 | ⤷ Try a Trial | |||
Austria | 404173 | ⤷ Try a Trial | |||
Austria | 404184 | ⤷ Try a Trial | |||
Austria | 406878 | ⤷ Try a Trial | |||
Austria | 415155 | ⤷ Try a Trial | |||
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