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Last Updated: July 26, 2021

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Details for Patent: 8,067,431


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Which drugs does patent 8,067,431 protect, and when does it expire?

Patent 8,067,431 protects MOVANTIK and is included in one NDA.

This patent has forty-two patent family members in twenty-four countries.

Summary for Patent: 8,067,431
Title:Chemically modified small molecules
Abstract: Methods of modifying the rate of systemic absorption of a drug administered to a subject by a pulmonary route, the method comprising covalently conjugating a hydrophilic polymer to a drug, wherein the drug has a half-life of elimination from the lung of less than about 180 minutes, to form a drug-polymer conjugate, wherein the drug-polymer conjugate has a net hydrophilic character and a weight average molecular weight of from about 50 to about 20,000 Daltons, and wherein the half-life of elimination from the lung of the drug-polymer conjugate is at least about 1.5-fold greater than the half-life of elimination from the lung of the drug, wherein the half-life of elimination from the lung is measured by bronchoalveolar lavage followed by assaying residual lung material.
Inventor(s): Fishburn; C. Simone (Redwood City, CA), Lechuga-Ballesteros; David (San Jose, CA), Viegas; Tacey (Madison, AL), Kuo; Mei-Chang (Palo Alto, CA), Song; Yuan (Belmont, CA), Gursahani; Hema (Foster City, CA), Leach; Chester (Tijeras, NM)
Assignee: Nektar Therapeutics (San Francisco, CA)
Application Number:12/710,167
Patent Claim Types:
see list of patent claims
Use; Dosage form;

Drugs Protected by US Patent 8,067,431

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Redhill MOVANTIK naloxegol oxalate TABLET;ORAL 204760-001 Sep 16, 2014 RX Yes No ⤷  Free Forever Trial ⤷  Free Forever Trial TREATMENT OF OPIOID-INDUCED CONSTIPATION ⤷  Free Forever Trial
Redhill MOVANTIK naloxegol oxalate TABLET;ORAL 204760-002 Sep 16, 2014 RX Yes Yes ⤷  Free Forever Trial ⤷  Free Forever Trial TREATMENT OF OPIOID-INDUCED CONSTIPATION ⤷  Free Forever Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 8,067,431

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2004299138 ⤷  Free Forever Trial
Australia 2010202277 ⤷  Free Forever Trial
Australia 2012227249 ⤷  Free Forever Trial
Australia 2014280956 ⤷  Free Forever Trial
Canada 2549730 ⤷  Free Forever Trial
Canada 2758460 ⤷  Free Forever Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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Serving leading biopharmaceutical companies globally:

AstraZeneca
Medtronic
Colorcon
Mallinckrodt
Harvard Business School
Merck

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