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Serving leading biopharmaceutical companies globally:

Chinese Patent Office
US Department of Justice
Healthtrust
Cipla
Cantor Fitzgerald
Argus Health
Fish and Richardson
Cerilliant
UBS
Boehringer Ingelheim

Generated: February 19, 2018

DrugPatentWatch Database Preview

Details for Patent: 8,058,238

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Summary for Patent: 8,058,238
Title:High purity lipopeptides
Abstract: The invention discloses highly purified daptomycin and to pharmaceutical compositions comprising this compound. The invention discloses a method of purifying daptomycin comprising the sequential steps of anion exchange chromatography, hydrophobic interaction chromatography and anion exchange chromatography. The invention also discloses a method of purifying daptomycin by modified buffer enhanced anion exchange chromatography. The invention also discloses an improved method for producing daptomycin by fermentation of Streptomyces roseosporus. The invention also discloses high pressure liquid chromatography methods for analysis of daptomycin purity. The invention also discloses lipopeptide micelles and methods of making the micelles. The invention also discloses methods of using lipopeptide micelles for purifying lipopeptide antibiotics, such as daptomycin. The invention also discloses using lipopeptide micelles therapeutically.
Inventor(s): Kelleher; Thomas (Weston, MA), Lai; Jan-Ji (Westborough, MA), DeCourcey; Joseph P. (Charlestown, MA), Lynch; Paul (Arlington, MA), Zenoni; Maurizio (Milan, IT), Tagliani; Auro (Pavia, IT)
Assignee: Cubist Pharmaceuticals, Inc. (Lexington, MA)
Application Number:11/739,180
Patent Claim Types:
see list of patent claims
Composition; Process; Formulation; Use;

Drugs Protected by US Patent 8,058,238

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Patents Family Members for US Patent 8,058,238

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Serving hundreds of leading biopharmaceutical companies globally:

Healthtrust
Federal Trade Commission
McKinsey
Harvard Business School
Medtronic
Cipla
Fuji
UBS
Covington

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