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|Title:||Parenteral CCI-779 formulations containing cosolvents, an antioxidant, and a surfactant|
|Abstract:||Parenteral formulations of rapamycin 42-ester with 3-hydroxy-2-(hydroxymethyl) -2-methylpropionic acid (CCI-779) are provided. One parenteral formulation contains CCI-779, an alcoholic co-solvent, and an antioxidant. Another parenteral formulation contains CCI-779, an alcoholic solvent, an antioxidant, a diluent solvent, and a surfactant. Processes for preparing parenteral CCI-779 formulations using a co-solvent concentrate are also provided.|
|Inventor(s):||Rubino; Joseph T. (Towaco, NJ), Siskavich; Victoria (Lyon Mountain, NY), Harrison; Maureen M. (Sugar Loaf, NY), Gandhi; Pooja (Highland Mills, NY)|
|Assignee:||Wyeth LLC (Madison, NJ)|
Patent Claim Types:|
see list of patent claims
|Composition; Compound; Process;|
Back Citations: 105th percentile
Forward Citations: 5th percentile
|Applicant||Tradename||Generic Name||Dosage||NDA||Approval Date||Type||RLD||Patent No.||Patent Expiration||Product||Substance||Delist Req.||Patented / Exclusive Use|
Pf Prism Cv
|SOLUTION;INTRAVENOUS||022088-001||May 30, 2007||RX||Yes||8,026,276*PED||► subscribe||Y|
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