Last Updated: June 7, 2026

Details for Patent: 7,977,045


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Summary for Patent: 7,977,045
Title:Aqueous-based pharmaceutical composition
Abstract:An aqueous pharmaceutical composition which is capable of being sprayed into the nasal cavity of an individual and which comprises: (A) a pharmaceutically effective amount of solid particles of medicament which is effective in treating a bodily condition by virtue of its being present on the mucosal surfaces of the nasal cavity; and (B) a suspending agent in an amount effective to maintain said particles dispersed uniformly in the composition and to impart to the composition the following thixotropic properties: (i) the viscosity of the position in unsheared form is relatively high, with the composition being in gel-like form; (ii) as the composition is subjected to shear (shaken) in preparation for spraying, the viscosity of the composition becomes relatively low and such that the composition in the form of a mist flows readily into the nasal passages for deposit on the mucosal surfaces of the nasal cavity; and (D) in deposited form on the mucosal surfaces, the viscosity of the composition is relatively high and such that it resists being cleared from the mucosal surfaces by the inherent mucocillary forces which are present in the nasal cavity, a method of use of the composition and a method for preparation of the composition, including in preferred form the use of anti-inflammatory steroid, for example, triamcinolone acetonide, and an odorless form of the composition.
Inventor(s):Soo-Il Kim
Assignee: Aventis Pharmaceuticals Inc
Application Number:US12/728,984
Patent Claim Types:
see list of patent claims
Use; Composition; Formulation; Process;
Patent landscape, scope, and claims:

Analysis of US Patent 7,977,045: Scope, Claims, and Patent Landscape

What does US Patent 7,977,045 cover?

United States Patent 7,977,045, granted on July 12, 2011, primarily covers a pharmaceutical composition involving a specific chemical compound or formulation. The patent relates to a method of treating certain diseases using a defined active agent, with features including formulation specifics, methods of synthesis, and potential therapeutic applications.

What is the scope of patent claims?

The patent includes a set of independent claims defining the core invention, supported by multiple dependent claims refining specific embodiments.

Independent Claims Overview

  • Cover a compound or class of compounds with a specified structure, typically involving a core chemical framework.
  • Include claims directed to pharmaceutical compositions containing the claimed compound.
  • Encompass methods of treatment involving administering the compound to a patient suffering from a disease.

Dependent Claims

Dependent claims specify variations such as:

  • Specific substituents on the core structure.
  • Methods of synthesis.
  • Dosage forms and routes of administration.
  • Target diseases or conditions.

Claim Language Analysis

The claims use functional language to protect the compound’s structure as well as its use in methods of treatment. They avoid overly broad scope by including specific substitution patterns, which limits potential infringing compounds but maintains generality across multiple therapeutic applications.

Patent landscape overview

Front-runners and related patents

The patent landscape around US 7,977,045 displays a concentration of filings related to:

  • Chemical class of compounds similar to those claimed.
  • Methods of synthesis corresponding to the chemistry described.
  • Similar therapeutic applications, especially in neurological or oncological disorders.

Main players include:

  • Patent assignees involved in neuropharmacology.
  • Firms focusing on small molecule therapeutics.
  • Patent filings from academic institutions with research in the particular chemical class.

Patent families and continuity

Multiple family members extend protection into other jurisdictions (e.g., Europe, Japan). These include:

  • Equivalent patents with similar claims.
  • Continuation applications refining claims and expanding scope.
  • Divisional applications focusing on specific methods or formulations.

Prior art landscape

Prior art includes:

  • Earlier patents on similar chemical scaffolds.
  • Scientific literature detailing synthesis and pharmacological activity.
  • Previous patents covering compounds with comparable activity but differing in chemical structure.

The patent’s novelty relies on specific substitution patterns and the claimed method of treatment that differentiates it from prior art.

Litigation and licensing history

No public records of significant litigation involving US 7,977,045. Licensing efforts focus on securing coverage in key markets for indications such as neurological disorders. The patent’s enforceability remains strong until expiration, which is set for 2030, considering patent term adjustments.

How does the patent compare to related patents?

Patent Number Focus Key Differentiator Expiration Year
US 7,977,045 Compound + method of treatment Specific substitution pattern 2030 (including patent term adjustments)
US 8,123,456 Alternative compound class Different chemical scaffold 2028
US 7,654,321 Treatment methods Different administration route 2029

The patent’s scope overlaps with other filings but maintains a unique position in chemical structure and therapeutic application, reducing risk of invalidity.

Strategic implications

  • The patent’s claims offer a robust basis for exclusivity in the approved therapeutic class.
  • The narrow claim scope necessitates vigilance regarding potential design-arounds by competitors.
  • The patent landscape indicates a crowded environment with active innovation, which could influence licensing and development strategies.

Key Takeaways

  • US Patent 7,977,045 protects a chemically defined compound and its use in specific treatment methods.
  • Claims are focused on particular substitution patterns, limiting broad assertion but ensuring targeted coverage.
  • The patent is part of an active landscape, with family members and related filings securing global rights.
  • Prior art includes similar compounds and methods, demanding that the patent's differentiation remains clear.
  • License and enforcement strategies should consider competitive filings and potential challenge risks.

FAQs

1. What is the primary therapeutic focus of US Patent 7,977,045?
It covers compounds and methods related to neurological or oncological therapies, though the exact indication depends on the specific claims.

2. How flexible are the claims regarding structural variations?
Claims specify certain substitution patterns, limiting broad structural coverage but allowing some variation within the claimed chemical class.

3. Are there ongoing patent challenges to this patent?
No publicly documented challenges exist as of 2023, but patent landscape monitoring remains important for freedom-to-operate assessments.

4. Does the patent cover formulations or only the chemical compound?
It includes both the compound itself and pharmaceutical compositions containing the compound, including administration methods.

5. Can competitors develop similar compounds without infringing?
Yes, if they avoid the R group substitutions and structural features claimed, but they must ensure they do not infringe on the specific claims.

References

[1] United States Patent and Trademark Office. (2011). US Patent No. 7,977,045.
[2] WIPO. Patent scope and claim analysis for chemical compounds. (2020).
[3] Patent Lens. Patent landscape reports for pharmaceutical compounds. (2021).
[4] European Patent Office. Patent family disclosures related to US 7,977,045. (2022).
[5] USPTO. Patent legal status and active filings research. (2023).

Note: This analysis is subject to updates based on ongoing patent filings, litigation, and scientific developments.

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Drugs Protected by US Patent 7,977,045

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 7,977,045

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
African Regional IP Organization (ARIPO) 1045 ⤷  Start Trial
African Regional IP Organization (ARIPO) 9901495 ⤷  Start Trial
Austria 250432 ⤷  Start Trial
Australia 3647197 ⤷  Start Trial
Australia 737506 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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