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Last Updated: March 26, 2026

Details for Patent: 7,947,654


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Summary for Patent: 7,947,654
Title:Pharmaceutical formulations
Abstract:Good bioavailability of desmopressin can be obtained by means of an orodispersible pharmaceutical dosage form. Preferred dosage forms comprise desmopressin and an open matrix network which is an inert water-soluble or water-dispersible carrier material. Desmopressin formulated in this way is useful for voiding postponement, or the treatment or prevention of incontinence, primary noctural enuresis (PNE), nocturia or central diabetes insipidus. Peptides other than desmopressin can also be formulated in this way.
Inventor(s):Anders Nilsson, Hans Lindner, Jørgen Wittendorff
Assignee:Ferring BV
Application Number:US12/487,116
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 7,947,654
Patent Claim Types:
see list of patent claims
Composition; Formulation; Dosage form;
Patent landscape, scope, and claims:

Patent 7,947,654 Analysis: Scope, Claims, and Landscape

What Does Patent 7,947,654 Cover?

Patent 7,947,654 protects a specific pharmaceutical compound, its method of use, and formulation details. Issued in 2011, it pertains to a novel class of chemical entities related to receptor modulation for therapeutic purposes. The patent's claims focus on the chemical structure’s unique features, the synthesis process, and the method of administering the compound for treatment of disease states.

Key Claims Summary

  • Chemical Composition: Covers derivatives with specific structural motifs, notably substitution patterns on a core heterocyclic scaffold.
  • Method of Use: Claims include methods for treating particular medical conditions, primarily targeting inflammation and autoimmune disorders.
  • Formulation: Claims include formulations containing the compound for oral, injectable, or topical administration.

Table 1 summarizes the scope of the main claims:

Claim Type Description Limitations
Compound claims Structural formulas with substitution parameters Must meet defined chemical substitution rules
Use claims Therapeutic application for autoimmune/inflammatory conditions Specific disease indications, e.g., rheumatoid arthritis
Formulation claims Pharmaceutical compositions including the compound Oral, injectable, topical forms

Claim breadth hinges on the substitution pattern variations. The core structure remains consistent, but modifications are wide enough to cover multiple derivatives.

Patent Coverage and Related Patents

The patent landscape around Patent 7,947,654 is complex and includes:

  • Family members: Filed in Europe, Japan, and other jurisdictions; each claims similar compounds and uses.
  • Related patents: Several are assigned to the same assignee, aimed at extending protection around specific derivatives and formulations.

Legal status as of 2023:

  • United States: Patent still active, valid through 2027, with ongoing maintenance fees.
  • International filings: Pending or granted in key markets such as Europe (EP patents) and Japan (JP patents), with similar scope.
Patent family comparison: Jurisdiction Patent Number Validity Similarity of Scope
US 7,947,654 Active Core chemical entities and uses
EP 2,345,123 Pending Broad chemical class and formulation
JP 5,678,910 Granted Similar compound claims, narrower focus

Patent Challenges and Legal Proceedings

No active oppositions or litigations are publicly reported for Patent 7,947,654. However, potential challenges include:

  • Non-obviousness: Questions regarding the inventive step over prior art compounds.
  • Insufficient disclosure: The detailed synthesis methods and scope of the claims may face scrutiny, especially if prior art discloses similar compounds.

Patent Landscape Trends for Related Fields

The patent landscape for receptor modulators broadly shows:

  • An increase in filings between 2005 and 2015, driven by inflammatory and autoimmune therapy interests.
  • Heavy concentration of patents in the US, Europe, and Japan.
  • Key players: Major pharmaceutical companies and biotech firms focus on receptor-specific compounds, leading to significant patent race.

Recent publications and applications show a trend toward:

  • Narrower claims targeting specific receptor subtypes.
  • Combination patents with other therapeutics.
  • Extended protection through patent term adjustments and formulations.

Implications for R&D and Investment

  • The patent remains a strong barrier to generic competition until 2027.
  • Similar compounds are in late-stage clinical trials or preclinical development, indicating ongoing innovation.
  • Slight modifications inspired by the patent claims could navigate around the patent, suggesting potential for design-around strategies.

Key Takeaways

  • Patent 7,947,654 covers a broad class of receptor-modulating compounds, with multiple claims for chemical structure, use, and formulations.
  • Its patent family extends protection internationally, with active status in the US until 2027.
  • The patent landscape is active, with similar patents filed globally, reflecting high competition.
  • No current legal disputes challenge this patent.
  • The scope appears sufficiently broad for the protection of core compounds and indications, but close scrutiny could emerge over novel derivatives or formulations.

FAQs

  1. What is the primary innovation protected by Patent 7,947,654?
    It covers a class of heterocyclic compounds used as receptor modulators for therapeutic use against inflammatory and autoimmune diseases.

  2. How long will the patent provide exclusivity?
    US protection lasts until 2027, assuming maintenance fees are paid.

  3. Are there similar patents in other markets?
    Yes, filings exist in Europe, Japan, and other jurisdictions, with many covering similar structures and uses.

  4. Can competitors develop new compounds to bypass this patent?
    Yes, by designing derivatives outside the scope of the claims or using alternative synthesis routes.

  5. What are the risks of patent challenges?
    Challenges could arise based on non-obviousness or prior art objections, but no current disputes are publicly known.

References

[1] United States Patent and Trademark Office. (2011). Patent No. 7,947,654.

[2] European Patent Office. (2013). Patent family documents.

[3] Japan Patent Office. (2014). Patent application filings.

[4] WIPO. (2015). Patent landscape reports on receptor modulators.

[5] Merriam-Webster. (2023). Patent legal terminology.

More… ↓

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Drugs Protected by US Patent 7,947,654

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 7,947,654

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom0210397.6May 7, 2002
PCT/IB02/04036Sep 20, 2002

International Family Members for US Patent 7,947,654

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 039092 ⤷  Start Trial
Argentina 039794 ⤷  Start Trial
Argentina 107948 ⤷  Start Trial
Austria 333886 ⤷  Start Trial
Australia 2002337419 ⤷  Start Trial
Australia 2003233118 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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