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Boehringer Ingelheim

Last Updated: July 28, 2021

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Details for Patent: 7,777,050

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Summary for Patent: 7,777,050
Title:N3 alkylated benzimidazole derivatives as MEK inhibitors
Abstract: Disclosed are compounds of the Formula I ##STR00001## and pharmaceutically acceptable salts and prodrugs thereof, wherein W, R.sup.1, R.sup.2, R.sup.7, R.sup.8, R.sup.9 and R.sup.10 are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals. Also disclosed is a method of using such compounds in the treatment of hyperproliferative diseases in mammals, and pharmaceutical compositions containing such compounds.
Inventor(s): Wallace; Eli M. (Lyons, CO), Lyssikatos; Joseph P. (Superior, CO), Marlow; Allison L. (Boulder, CO), Hurley; T. Brian (Boulder, CO)
Assignee: Array BioPharma Inc. (Boulder, CO)
Application Number:12/050,827
Patent Claim Types:
see list of patent claims
Composition; Compound;

Drugs Protected by US Patent 7,777,050

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Array Biopharma Inc MEKTOVI binimetinib TABLET;ORAL 210498-001 Jun 27, 2018 RX Yes Yes ⤷  Free Forever Trial ⤷  Free Forever Trial Y Y ⤷  Free Forever Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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