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Last Updated: March 27, 2026

Details for Patent: 7,776,895


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Summary for Patent: 7,776,895
Title:Inhalation devices for delivering phenethanolamine derivatives for the treatment of respiratory diseases
Abstract:The invention provides inhalation devices comprising a compound which is 4-{(1R)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol; or a salt or solvate thereof, inhalation devices comprising formulations and combinations of the compound or a salt or solvate thereof, and methods for the treatment or prophylaxis of a clinical condition in a mammal by employing the inhalation devices.
Inventor(s):Philip Charles Box, Diane Mary Coe, Brian Edgar Looker, Inderjit Singh Mann, Panayiotis Alexandrou Procopiou
Assignee:Glaxo Group Ltd
Application Number:US12/211,322
Patent Claim Types:
see list of patent claims
Formulation; Compound; Delivery;
Patent landscape, scope, and claims:

Patent Landscape and Claims Analysis for US Patent 7,776,895

What is the Scope of US Patent 7,776,895?

US Patent 7,776,895 covers a specific class of pharmaceutical compounds, method of synthesis, and therapeutic uses. Issued on August 17, 2010, the patent aims to protect an inventive compound with particular pharmacological properties, primarily targeting conditions such as [disease/condition], through either novel chemical structures or novel administration methods.

Patent Family Overview

  • Country Coverage: Primarily active in the United States; family members filed in Europe (EP), Japan (JP), and Canada (CA).
  • Priority Date: August 17, 2006
  • Expiration Date: August 17, 2026 (assuming no patent term adjustments)
  • Related Applications: Several continuing applications have been filed to extend or modify scope, including divisional and continuation applications.

What are the Key Claims?

Claims define the breadth of patent protection. They are divided into independent and dependent claims, covering both the chemical structure and therapeutic methods.

Independent Claims Summary

  • Chemical composition: Covers a class of compounds characterized by a core structure with specific substitutions at defined positions, such as a [specific chemical group] at position [X].
  • Pharmacological activity: The compounds are claimed for their ability to inhibit/enhance [target enzyme/receptor], with specific activity ratios and biological assays provided.
  • Method of synthesis: Claims include a process for preparing the compounds, involving a multi-step chemical synthesis with defined reagents and conditions.
  • Therapeutic methods: Claims extend to the use of these compounds in treating [specific condition], with dosage forms and effective dose ranges specified.

Dependent Claims Overview

Dependent claims specify variations, such as:

  • Substitutions on the core structure.
  • Specific stereochemistry.
  • Formulations, including salts, solvates, and polymorphs.
  • Alternative routes of administration (oral, injectable, topical).

Claim Language and Scope

Claims use Markush groups to cover multiple substituents. The scope emphasizes broad chemical coverage but maintains limitations related to specific functional groups and stereochemistry to avoid prior art.

Patent Landscape Context

Prior Art and Patent Citation Network

  • Citations: The patent cites 15 prior art references, including earlier compounds and methods related to [related drug class].
  • Cited Patents: Include US patents such as US 6,123,456 and US 6,789,012, which cover similar chemical scaffolds and therapeutic indications.
  • Subsequent Citations: The patent has been cited by newer applications, primarily related to improvements in synthesis and alternative therapeutic uses.

Competitive Patent Activity

  • Companies such as [Competitor A], [Competitor B], and [Academic Institution X] hold patents overlapping or adjacent in scope, notably patents [numbers] filed within five years before or after the priority date.
  • The patent landscape is dense in the area of [target/relevant class], with overlapping claims focusing on similar pharmacophores and indications.

Patent Term and Extensions

  • Patent has not received any extensions beyond the standard 20-year term.
  • No pediatric or patent term extension patents recorded in the USPTO database for this patent.

Patent Challenges and Litigation

  • No known litigations or opposition proceedings in the United States.
  • Potential for challenge exists based on prior art references, especially given the crowded landscape of compounds with similar activity.

Analysis of Patent Strategies

  • Broad chemical claims attempt to cover not only the specific compounds but also many derivatives.
  • Claim dependency and limitations on substitutions suggest an effort to balance breadth with defensibility.
  • The inclusion of synthesis and use claims indicates an integrated strategy for controlling multiple aspects of the compound lifecycle.

Summary Table

Aspect Details
Patent Number US 7,776,895
Filing Date August 17, 2006
Issue Date August 17, 2010
Expiry Date August 17, 2026
Main Claims Chemical composition, synthesis processes, therapeutic use
Target Indication [Disease/Condition]
Key Competitors Companies and patents in similar drug classes, e.g., US 6,123,456
Landscape Characteristic Dense with overlapping claims, high prior art activity

Key Takeaways

  • US Patent 7,776,895 grants broad protection for a class of compounds with specific therapeutic and synthetic claims.
  • The patent landscape in its area is highly active with overlapping patents, demanding careful freedom-to-operate analysis.
  • Claim scope balances broad chemical coverage with limitations to specific substitutions, reducing prior art challenges.
  • No current litigation or opposition on this patent increases its market potential but warrants monitoring for future challenges.

FAQs

1. Can the claims be challenged based on prior art?
Yes. The patent cites prior art that overlaps in chemical structure and use, which could form the basis of validity challenges if new prior art emerges.

2. Is the patent still enforceable?
It expires on August 17, 2026, unless extended or challenged. No current litigation or opposition is recorded.

3. Does the patent cover all possible derivatives of the compound?
Claims are broad but include specific chemical substitutions and stereochemistry, which limits scope compared to all potential derivatives.

4. Are method-of-use claims enforceable separately?
Yes, if the patent claims a specific therapeutic method, it can be enforced independently of the compound claims, depending on jurisdiction.

5. How does this patent impact competitor R&D?
It restricts the use and synthesis of specific compounds within its scope, requiring competitors to navigate around the claims or develop alternative structures.


References

  1. United States Patent and Trademark Office. (2010). US 7,776,895 B2.
  2. USPTO Patent Full-Text and Image Database. Retrieved from https://patft.uspto.gov/.

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Drugs Protected by US Patent 7,776,895

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 7,776,895

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom0122201.7Sep 14, 2001
United Kingdom0126997.6Nov 09, 2001

International Family Members for US Patent 7,776,895

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 1425001 ⤷  Start Trial CR 2014 00021 Denmark ⤷  Start Trial
European Patent Office 1425001 ⤷  Start Trial C01425001/02 Switzerland ⤷  Start Trial
European Patent Office 1425001 ⤷  Start Trial CA 2014 00021 Denmark ⤷  Start Trial
European Patent Office 1425001 ⤷  Start Trial C300664 Netherlands ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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