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Generated: September 25, 2017
| Title: | Remedy for overactive bladder comprising acetic acid anilide derivative as the active ingredient |
| Abstract: | (R)-2-(2-aminothiazol-4-yl)-4'-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]a- cetic acid anilide or its salt shows a potent bladder relaxation effect in "isolated rat bladder smooth muscle relaxation test", dose-dependently lowers the contraction frequency of rhythmic bladder contractions in "rat rhythmic bladder contraction measurement test" and, moreover, prolongs the urination intervals in "urination functions measurement test on cyclophosphamide-induced overactive bladder model rat". Owing to these effects, the above compound is useful as a remedy for ovaractive bladder. |
| Inventor(s): | Takasu; Toshiyuki (Tsukuba, JP), Sato; Shuichi (Tsukuba, JP), Ukai; Masashi (Tsukuba, JP), Maruyama; Tatsuya (Tsukuba, JP) |
| Assignee: | Astellas Pharma Inc. (Tokyo, JP) |
| Application Number: | 10/534,290 |
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Patent Claim Types: see list of patent claims | Use; |
| Foriegn Application Priority Data | ||
| Foreign Country | Foreign Patent Number | Foreign Patent Date |
| Japan | 2002-323792 | Nov 07, 2002 |
| PCT Information | |||
| PCT Filed | November 04, 2003 | PCT Application Number: | PCT/JP03/14065 |
| PCT Publication Date: | May 21, 2004 | PCT Publication Number: | WO2004/041276 |
| Country | Document Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| China | 1711085 | ► Subscribe | |||||||||||||
| China | 100406011 | ► Subscribe | |||||||||||||
| Cyprus | 1111399 | ► Subscribe | |||||||||||||
| Germany | 60336334 | ► Subscribe | |||||||||||||
| Denmark | 1559427 | ► Subscribe | |||||||||||||
| European Patent Office | 1559427 | ► Subscribe | C300599 | Netherlands | ► Subscribe | ||||||||||
| European Patent Office | 1559427 | ► Subscribe | CA 2013 00028 | Denmark | ► Subscribe | ||||||||||
| European Patent Office | 1559427 | ► Subscribe | 92218 | Luxembourg | ► Subscribe | ||||||||||
| European Patent Office | 1559427 | ► Subscribe | 13C0032 | France | ► Subscribe | ||||||||||
| European Patent Office | 1559427 | ► Subscribe | 1390028-7 | Sweden | ► Subscribe | ||||||||||
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
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