(Thio) carbamoyl-cyclohexane derivatives as D3/D2 receptor antagonists
The present invention relates to new D3 and D2 dopamine receptor subtype preferring ligands of formula (I): ##STR00001## wherein R.sub.1 and R.sub.2 represent independently a substituent selected from hydrogen, alkyl, aryl, cycloalkyl, aroyl, or R.sub.1 and R.sub.2 may form a heterocyclic ring with the adjacent nitrogen atom; X represents an oxygen or sulphur atom; n is an integer of from 1 to 2, and/or geometric isomers and/or stereoisomers and/or diastereomers and/or salts and/or hydrates and/or solvates thereof, to the processes for producing the same, to pharmaceutical compositions containing the same and to their use in therapy and/or prevention of a condition which requires modulation of dopamine receptors.
Againe Csongor; Eva (Budapest, HU), Galambos; Janos (Budapest, HU), Nogradi; Katalin (Budapest, HU), Vago; Istvan (Budapest, HU), Gyertyan; Istvan (Budapest, HU), Kiss; Bela (Budapest, HU), Laszlovszky; Istvan (Budapest, HU), Laszy; Judit (Nagykovacsi, HU), Saghy; Katalin (Budapest, HU)
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