Last Updated: August 25, 2026

Details for Patent: 7,737,142


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Which drugs does patent 7,737,142 protect, and when does it expire?

Patent 7,737,142 protects VRAYLAR and is included in one NDA.

Protection for VRAYLAR has been extended six months for pediatric studies, as indicated by the *PED designation in the table below.

This patent has forty-five patent family members in thirty-four countries.

Summary for Patent: 7,737,142
Title:(Thio) carbamoyl-cyclohexane derivatives as D3/D2 receptor antagonists
Abstract:The present invention relates to new D3 and D2 dopamine receptor subtype preferring ligands of formula (I): wherein R1 and R2 represent independently a substituent selected from hydrogen, alkyl, aryl, cycloalkyl, aroyl, or R1 and R2 may form a heterocyclic ring with the adjacent nitrogen atom; X represents an oxygen or sulphur atom; n is an integer of from 1 to 2, and/or geometric isomers and/or stereoisomers and/or diastereomers and/or salts and/or hydrates and/or solvates thereof, to the processes for producing the same, to pharmaceutical compositions containing the same and to their use in therapy and/or prevention of a condition which requires modulation of dopamine receptors.
Inventor(s):Eva Againe Csongor, Janos Galambos, Katalin Nogradi, Istvan Vago, Istvan Gyertyan, Bela Kiss, Istvan Laszlovszky, Judit Laszy, Katalin Saghy
Assignee: Richter Gedeon Nyrt
Application Number:US11/337,275
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 7,737,142
Patent Claim Types:
see list of patent claims
Use; Composition;

Drugs Protected by US Patent 7,737,142

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Abbvie VRAYLAR cariprazine hydrochloride CAPSULE;ORAL 204370-005 Dec 18, 2025 RX Yes No ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
Abbvie VRAYLAR cariprazine hydrochloride CAPSULE;ORAL 204370-006 Dec 18, 2025 RX Yes No ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
Abbvie VRAYLAR cariprazine hydrochloride CAPSULE;ORAL 204370-001 Sep 17, 2015 RX Yes Yes ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
Abbvie VRAYLAR cariprazine hydrochloride CAPSULE;ORAL 204370-002 Sep 17, 2015 RX Yes No ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
Abbvie VRAYLAR cariprazine hydrochloride CAPSULE;ORAL 204370-003 Sep 17, 2015 RX Yes No ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
Abbvie VRAYLAR cariprazine hydrochloride CAPSULE;ORAL 204370-004 Sep 17, 2015 RX Yes No ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 7,737,142

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
HungaryP0302451Aug 4, 2003

International Family Members for US Patent 7,737,142

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 1663996 ⤷  Start Trial PA2017027 Lithuania ⤷  Start Trial
European Patent Office 1663996 ⤷  Start Trial CR 2017 00042 Denmark ⤷  Start Trial
European Patent Office 1663996 ⤷  Start Trial 122017000083 Germany ⤷  Start Trial
European Patent Office 1663996 ⤷  Start Trial 300913 Netherlands ⤷  Start Trial
European Patent Office 1663996 ⤷  Start Trial 47/2017 Austria ⤷  Start Trial
European Patent Office 1663996 ⤷  Start Trial LUC00039 Luxembourg ⤷  Start Trial
European Patent Office 1663996 ⤷  Start Trial 2017C/045 Belgium ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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