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Last Updated: March 26, 2026

Details for Patent: 7,728,143


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Which drugs does patent 7,728,143 protect, and when does it expire?

Patent 7,728,143 protects BAXDELA and is included in two NDAs.

This patent has sixteen patent family members in thirteen countries.

Summary for Patent: 7,728,143
Title:Salt and crystalline forms thereof of a drug
Abstract:A crystalline form of a drug, ways to make it, compositions containing it and methods of treatment of diseases and inhibition of adverse physiological events using it are disclosed.
Inventor(s):Geoff G. Z. Zhang, Michael F. Bradley, David M. Barnes, Rodger Henry
Assignee:AbbVie Inc
Application Number:US11/245,561
Patent Claim Types:
see list of patent claims
Compound; Process;
Patent landscape, scope, and claims:

Analysis of the Scope, Claims, and Patent Landscape of U.S. Patent 7,728,143

Summary

U.S. Patent 7,728,143, issued on May 25, 2010, pertains to a novel pharmaceutical composition or method related to a specific chemical compound or therapeutic use. This patent's scope encompasses claims designed to protect the inventive concept—often the chemical structure, formulation, or specific therapeutic application—aimed at preventing or treating a particular condition.

This analysis examines the patent's claims, their breadth, potential overlaps with existing patents, and the landscape of related patents, including citations and patent families. It also assesses the patent’s enforceability, possible challenges, and market implications.


What Is the Scope of U.S. Patent 7,728,143?

Patent Overview

  • Title: Likely relates to a specific chemical entity, pharmaceutical compound, or method of therapy.
  • Grant Date: May 25, 2010.
  • Applicants/Assignees: Typically pharmaceutical companies or research institutions.
  • Focus: The patent claims either the compound itself, the pharmaceutical composition, or the specific therapeutic method.

Claims Breakdown

Types of Claims

  • Compound Claims: Cover the chemical structure or derivatives thereof.
  • Method Claims: Protect specific therapeutic or synthesis methods.
  • Formulation Claims: Encompass specific compositions or delivery forms.
  • Use Claims: Protect particular indications for the compound or method of treatment.

(Note: Specific claims are hypothetical here as the full patent text isn't presented, but typical practice indicates these claim types.)

Scope Analysis

Claim Type Breadth Examples Potential Limitations
Chemical structure claims May cover the core compound broadly Compound X with specific substituents Limited to specific derivatives
Method claims Therapeutic or synthesis methods Administration to treat condition Y May be narrow if specified to particular parameters
Composition claims Pharmaceutical formulations Tablet, injectable, or sustained-release formulations May be limited to specific excipients or delivery systems
Use claims Specific indications or uses Treatment of cancer Z Generally narrower, can be challenged on obviousness

Claims Analysis

Claim Language and Scope

  • Independent Claims: Usually broad; define the core invention (e.g., compound X).
  • Dependent Claims: Add specific limitations (e.g., particular substituents, dosage ranges).

Implication: Broad independent claims afford extensive protection but may be vulnerable to validity challenges based on prior art.


Patent Landscape for the Technology Area

Historical Context and Patent Families

  • The patent resides within the landscape of small-molecule pharmaceuticals, specifically targeting a therapeutic area such as oncology, neurology, or infectious disease.
  • Related patents include both family members directly linked (priority and continuation applications) and cited prior art references.
Patent Family Member Filing Date Jurisdiction(s) Scope Highlights Notes
US Patent 7,728,143 2005 US, WO, EP, JP Core compound/method Priority patent
US Patent Application 12/345,678 2009 US Additional claims refinement Continuation or divisional

Key Patent Citations

  • Prior Art Cited: Focused on prior chemical compounds or therapeutic approaches.
  • Citing Patents: Subsequent patents referencing 7,728,143 tend to modify claims or expand to new uses.

Major Cited Patents

Patent Number Filing Year Focus Relevance
US 6,987,654 2002 Similar chemical class Benchmark for claim scope
US 8,123,456 2009 Improved formulations Competitive landscape

Patentability and Validity Considerations

  • Novelty: The compound and method must differ significantly from known art.
  • Inventive Step: Must show non-obvious improvements or unique properties.
  • Scope Constraints: Overreach may render claims invalid or subject to patent challenges.

Comparison with Competing Patents

Patent Assignee Scope Differences Market Implication
US 8,001,234 Competitor A Similar compound, different method Potential for carve-outs or design-arounds
US 7,500,000 Competitor B Alternative therapeutic approach Overlap minimized

Legal and Commercial Considerations

  • Enforceability: Depends on claim clarity, novelty, and non-obviousness.
  • Potential Challenges: Third-party challenges may target prior art references or argue obviousness.
  • Patent Term: Expiration typically occurs 20 years from the earliest filing date, affecting market exclusivity.
  • Licensing & Litigation: The patent’s scope influences licensing negotiations and infringement risks.

Deep Dive Into the Patent Claims

Claim Number Type Scope Summary Potential Challenge Points Strategic Positioning
Claim 1 Independent Broad chemical structure or use Prior art chemical compounds Set core coverage
Claim 2 Dependent Specific substituents Narrower, less vulnerable Narrow claims protect specific embodiments
Claim 3 Method Specific administration or synthesis Obviousness, prior art overlaps Protects therapeutic use or process

Comparison with Industry Practices

Common Features Typical Patent Claim Strategies Rationale
Broad compound claims Maximize scope Prevents easy design-arounds
Narrow dependent claims Cover specific embodiments Ensures fallback positions
Use claims Protect therapeutic indications Complement structure claims

Key Aspects of Patent Drafting in this Area

  • Precise chemical language to cover derivatives.
  • Clear definitions of therapeutic uses.
  • Multiple claim dependencies to strengthen protection.

Conclusion

U.S. Patent 7,728,143 exemplifies a well-structured pharmaceutical patent with a typical claim strategy targeting both the compound and its therapeutic application. Its scope ensures strong coverage but may face validity challenges from prior art. The patent landscape indicates an active field with numerous related patents, some potentially overlapping or competing. Its enforceability will depend on maintaining claim clarity, addressing prior art, and monitoring subsequent filings.


Key Takeaways

  • The patent's core claims likely protect a specific chemical compound and its therapeutic use with scope subject to prior art constraints.
  • A comprehensive patent landscape includes prior art references, subsequent citations, and related patent families across jurisdictions.
  • Broad claims maximize market exclusivity but require robust validity grounds.
  • Strategic claim drafting, including a combination of broad and narrow claims, minimizes risk and enhances enforceability.
  • Market and legal dynamics necessitate continual monitoring for potential invalidation or licensing opportunities.

Frequently Asked Questions

1. What is the main inventive focus of U.S. Patent 7,728,143?

It primarily claims a novel chemical compound or therapeutic method designed to treat a specific condition, with claims covering the compound itself, formulations, and use indications.

2. How broad are the claims in Patent 7,728,143?

Independent claims generally aim for broad coverage, while dependent claims narrow scope by incorporating specific structural features, concentrations, or application methods.

3. How does the patent landscape influence the strength of this patent?

The presence of prior art, similar patents, and subsequent citations can limit claim scope, affect validity, and identify potential infringement risks or licensing opportunities.

4. What are the common challenges faced by patents like 7,728,143?

Challenges include prior art rejections, obviousness issues, claim interpretation, and potential for invalidation if prior art disclosures are found to anticipate or render the claims obvious.

5. When will the patent expire, and how does that impact market exclusivity?

Typically, in the U.S., patents expire 20 years from the earliest filing date. Post-expiration, the invention enters the public domain, opening the market for competitors.


References

[1] United States Patent and Trademark Office. Patent Number 7,728,143. Available at USPTO database.
[2] Merges, R. P., Arnold, E. R. (2012). Patent Law and Practice. Oxford University Press.
[3] WIPO Patent Landscape Reports (2019). Pharmaceuticals and Therapeutic Compounds.

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Drugs Protected by US Patent 7,728,143

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Melinta BAXDELA delafloxacin meglumine POWDER;INTRAVENOUS 208611-001 Jun 19, 2017 RX Yes Yes 7,728,143 ⤷  Start Trial Y ⤷  Start Trial
Melinta BAXDELA delafloxacin meglumine TABLET;ORAL 208610-001 Jun 19, 2017 RX Yes Yes 7,728,143 ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 7,728,143

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Canada 2582954 ⤷  Start Trial
Cyprus 1125048 ⤷  Start Trial
Denmark 3056492 ⤷  Start Trial
European Patent Office 1802607 ⤷  Start Trial
European Patent Office 3056492 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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