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Details for Patent: 7,687,466

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Which drugs does patent 7,687,466 protect, and when does it expire?

Patent 7,687,466 protects VYVANSE and is included in two NDAs.

This patent has one hundred and forty-seven patent family members in twenty-six countries.

Summary for Patent: 7,687,466

Title:	Abuse-resistant amphetamine prodrugs
Abstract:	The invention describes compounds, compositions, and methods of using the same comprising a chemical moiety covalently attached to amphetamine. These compounds and compositions are useful for reducing or preventing abuse and overdose of amphetamine. These compounds and compositions find particular use in providing an abuse-resistant alternative treatment for certain disorders, such as attention deficit hyperactivity disorder (ADHD), ADD, narcolepsy, and obesity. Oral bioavailability of amphetamine is maintained at therapeutically useful doses. At higher doses bioavailability is substantially reduced, thereby providing a method of reducing oral abuse liability. Further, compounds and compositions of the invention decrease the bioavailability of amphetamine by parenteral routes, such as intravenous or intranasal administration, further limiting their abuse liability.
Inventor(s):	Mickle; Travis (Coralville, IA), Krishnan; Suma (Belvedere, CA), Bishop; Barney (Annandale, VA), Lauderback; Christopher (Blacksburg, VA), Moncrief; James Scott (Christiansburg, VA), Oberlender; Robert (Blacksburg, VA), Piccariello; Thomas (Blacksburg, VA), Paul; Bernhard J. (Lexington, MA), Verbicky; Christopher A. (Broadalbin, NY)
Assignee:	Shire LLC (Florence, KY)
Application Number:	12/201,794
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 7,687,466
Prior Art and Litigation Support	Order Prior Art and Litigation support for Patent 7,687,466
Patent Claim Types: see list of patent claims	Composition;

Drugs Protected by US Patent 7,687,466

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Shire Development	VYVANSE	lisdexamfetamine dimesylate	CAPSULE;ORAL	021977-007	Oct 30, 2014		RX	Yes	No			Y
Shire Development	VYVANSE	lisdexamfetamine dimesylate	CAPSULE;ORAL	021977-004	Dec 10, 2007		RX	Yes	No			Y
Shire Development	VYVANSE	lisdexamfetamine dimesylate	CAPSULE;ORAL	021977-001	Feb 23, 2007		RX	Yes	No			Y
Shire Development	VYVANSE	lisdexamfetamine dimesylate	CAPSULE;ORAL	021977-005	Dec 10, 2007		RX	Yes	No			Y

International Family Members for US Patent 7,687,466

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Austria	462411
Austria	462412
Austria	519502
Austria	533512