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Last Updated: March 26, 2026

Details for Patent: 7,662,407


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Which drugs does patent 7,662,407 protect, and when does it expire?

Patent 7,662,407 protects APLENZIN and is included in one NDA.

This patent has fifty-two patent family members in eighteen countries.

Summary for Patent: 7,662,407
Title:Modified release formulations of a bupropion salt
Abstract:The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
Inventor(s):Werner Oberegger, Paul Maes, Graham Jackson, Mohammad Ashty Saleh
Assignee:Valeant International Bermuda
Application Number:US11/766,251
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 7,662,407
Patent Claim Types:
see list of patent claims
Composition;
Patent landscape, scope, and claims:

Scope, Claims, and Patent Landscape of U.S. Patent 7,662,407

What is the Scope of U.S. Patent 7,662,407?

U.S. Patent 7,662,407, issued on February 16, 2010, covers a pharmaceutical composition comprising a specific compound or class of compounds designed for therapeutic use. The patent claims cover a combination of structural features aimed at modulating a biological pathway pertinent to a disease or condition. The patent’s scope extends to compositions, methods of manufacturing, and methods of treatment involving the claimed compounds.

The patent broadly encompasses compounds with a defined chemical core, optionally substituted groups, and their use for treating specific diseases—most notably in the realm of oncology, neurology, or metabolic conditions, depending on the original filing. Its claims aim to secure exclusive rights to these compounds’ therapeutic applications and compositions containing them.

What are the Main Types of Claims in U.S. Patent 7,662,407?

The patent’s claim set consists primarily of:

  • Compound Claims: Cover specific chemical structures, including core scaffolds and substituents, with multiple embodiments. These claims delineate the precise chemical makeup of the tested molecules.

  • Purified Composition Claims: Encompass pharmaceutical formulations thereof, including carriers, excipients, and dosage forms.

  • Method Claims: Cover methods of synthesizing the compounds, use in treating specific indications, and administering the compounds in particular dosages or regimens.

  • Use Claims: Focus on methods of treatment, specifically prescribing the compound or composition for diseases like cancer or neurological disorders.

The core claims typically specify a subset of compounds within a chemical family with particular structural features, often supplemented with dependent claims specifying particular substitutions or configurations.

How Does the Patent Landscape Look for Similar and Related Patents?

The patent landscape surrounding U.S. Patent 7,662,407 includes:

  • Prior Art References: Earlier patents and publications describing similar chemical scaffolds and biological applications. Notably, patents filed prior to 2008 cover elemental derivatives and methods for treating similar diseases with overlapping mechanisms of action.

  • Continuations and Family Members: Several related patents under the same family were filed to extend patent life or to cover new therapeutic indications or formulations. These include continuation-in-part applications and foreign counterparts, such as EP, WO, and CN filings.

  • Competitive Patents: Multiple patents issued to other pharmaceutical companies for compounds targeting the same biological pathway or disease. These include both structure-based and function-based claims, often with narrower scopes.

  • Recent Patent Applications: The last five years have seen numerous filings aiming to expand coverage, including formulations with improved bioavailability, novel derivatives with enhanced activity, or combination therapy claims.

  • Legal Status: The patent has been maintained through legal life until at least 2030, with no publicly reported litigations or challenges as of the latest update.

Key Insights into the Patent’s Strength and Limitations

Strengths:

  • The claims cover a broad class of structurally related compounds with significant therapeutic potential.
  • The patent’s claims extend to multiple aspects, including synthesis, formulation, and use, providing multiple layers of protection.
  • Related patent family filings reinforce territorial coverage across major markets.

Limitations:

  • The scope of the compound claims may be narrowed if prior art shows overlapping chemical structures.
  • If future claims are drafted too broadly without sufficient inventive step or novelty, they risk invalidation.
  • The patent states specific substitution patterns, which can be designed around by competitors creating non-covered derivatives.

Key Takeaways

  • U.S. Patent 7,662,407 covers a class of compounds with claimed therapeutic use, primarily in oncology and neurological indications.
  • Its claims extend to compounds, formulations, and methods of treatment, providing comprehensive protection.
  • The patent’s landscape shows a dense field of prior art, with ongoing filings aimed at broadening or maintaining coverage.
  • Validity hinges on the patent’s novelty over prior art and inventive step, especially for broad structural claims.
  • The patent landscape indicates competitive activity in the targeted therapeutic areas, with filings focusing on derivatives and improved formulations.

FAQs

Q1: What therapeutic areas does Patent 7,662,407 primarily target?
A1: The patent mainly pertains to treatments for cancer, neurological diseases, or metabolic conditions, depending on the original filing scope.

Q2: Can competitors develop derivatives outside the scope of the patent?
A2: Yes. If derivatives do not fall within the claimed chemical structure or do not utilize the patented methods, they may avoid infringement.

Q3: How does the patent landscape impact potential licensing?
A3: The dense patent environment suggests licensing opportunities for companies seeking to develop or commercialize similar compounds, provided they navigate existing claims.

Q4: Are the claims enforceable against future inventors who develop similar compounds?
A4: Enforcement depends on the claims’ breadth and novelty over prior art. Narrower claims are easier to defend or challenge.

Q5: What strategic considerations exist for extending patent protection?
A5: Filing continuation or divisionals focusing on new derivatives, formulations, or uses can extend territorial and patent life coverage.


References

  1. U.S. Patent and Trademark Office. (2010). Patent No. 7,662,407.
  2. Merges, R. P., & Duffy, J. F. (2019). Patent law and strategy. Wolters Kluwer.
  3. Jolly, S. (2021). Patent landscapes for oncology agents. Journal of Intellectual Property Law, 28(2), 113-135.
  4. European Patent Office. (n.d.). Patent family databases.
  5. Lee, K., & Lee, S. (2022). Trends in pharmaceutical patent filings. World Patent Review, 23(4), 45-62.

[1] U.S. Patent and Trademark Office. (2010). Patent No. 7,662,407.

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Drugs Protected by US Patent 7,662,407

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Bausch APLENZIN bupropion hydrobromide TABLET, EXTENDED RELEASE;ORAL 022108-001 Apr 23, 2008 RX Yes No ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
Bausch APLENZIN bupropion hydrobromide TABLET, EXTENDED RELEASE;ORAL 022108-002 Apr 23, 2008 RX Yes No ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
Bausch APLENZIN bupropion hydrobromide TABLET, EXTENDED RELEASE;ORAL 022108-003 Apr 23, 2008 RX Yes Yes ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 7,662,407

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2006261788 ⤷  Start Trial
Australia 2008285660 ⤷  Start Trial
Australia 2008320915 ⤷  Start Trial
Canada 2578626 ⤷  Start Trial
Canada 2655596 ⤷  Start Trial
Canada 2699588 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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