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Last Updated: September 26, 2022

Details for Patent: 7,498,343


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Which drugs does patent 7,498,343 protect, and when does it expire?

Patent 7,498,343 protects SIRTURO and is included in one NDA.

This patent has fifty-seven patent family members in thirty-five countries.

Summary for Patent: 7,498,343
Title:Mycobacterial inhibitors
Abstract: The present invention relates to novel substituted quinoline derivatives according to the general Formula (Ia) or the general Formula (Ib) ##STR00001## the pharmaceutically acceptable acid or base addition salts thereof, the stereochemically isomeric forms thereof, the tautomeric forms thereof and the N-oxide forms thereof. The claimed compounds are useful for the treatment of mycobacterial diseases, particularly those diseases caused by pathogenic mycobacteria such as Mycobacterium tuberculosis, M. bovis, M. avium and M. marinum. In particular, compounds are claimed in which, independently from each other, R.sup.1 is bromo, p=1, R.sup.2 is alkyloxy, R.sup.3 is optionally substituted naphthyl or phenyl, q=1, R.sup.4 and R.sup.5 each independently are hydrogen, methyl or ethyl, R.sup.6 is hydrogen, r is equal to 0 or 1 and R.sup.7 is hydrogen. Also claimed is a composition comprising a pharmaceutically acceptable carrier and, as active ingredient, a therapeutically effective amount of the claimed compounds, the use of the claimed compounds or compositions for the manufacture of a medicament for the treatment of mycobacterial diseases and a process for preparing the claimed compounds.
Inventor(s): Van Gestel; Jozef Frans Elisabetha (Beerse, BE), Guillemont; Jerome Emile Georges (Val de Reuil Cedex, FR), Venet; Marc Gaston (Le Mans, FR), Poignet; Herve Jean Joseph (Issy-les-Moulineaux Cedex 9, FR), Decrane; Laurence Francoise Bernadette (Val de Reuil Cedex, FR), Vernier; Daniel F. J. (Val de Reuil Cedex, FR), Odds; Frank Christopher (Drumoak, GB)
Assignee: Janssen Pharmaceutica N.V. (Beerse, BE)
Application Number:11/007,026
Patent Claim Types:
see list of patent claims
Compound; Composition; Use; Process;

Drugs Protected by US Patent 7,498,343

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Janssen Therap SIRTURO bedaquiline fumarate TABLET;ORAL 204384-002 May 27, 2020 RX Yes No See Plans and Pricing See Plans and Pricing Y Y TREATMENT OF PULMONARY MULTI-DRUG RESISTANT TUBERCULOSIS See Plans and Pricing
Janssen Therap SIRTURO bedaquiline fumarate TABLET;ORAL 204384-001 Dec 28, 2012 RX Yes Yes See Plans and Pricing See Plans and Pricing Y Y TREATMENT OF PULMONARY MULTI-DRUG RESISTANT TUBERCULOSIS See Plans and Pricing
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 7,498,343

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
African Regional IP Organization (ARIPO) 2421 See Plans and Pricing
Argentina 040673 See Plans and Pricing
Austria 463482 See Plans and Pricing
Australia 2003262529 See Plans and Pricing
Brazil 0312927 See Plans and Pricing
Brazil PI0312927 See Plans and Pricing
Canada 2493225 See Plans and Pricing
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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Serving leading biopharmaceutical companies globally:

Mallinckrodt
Boehringer Ingelheim
Medtronic
Express Scripts
Moodys
Colorcon

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