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Serving leading biopharmaceutical companies globally:

Queensland Health
Cantor Fitzgerald
Harvard Business School

Generated: December 11, 2017

DrugPatentWatch Database Preview

Details for Patent: 7,101,993

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Which drugs does patent 7,101,993 protect, and when does it expire?

Patent 7,101,993 protects SPINRAZA and KYNAMRO and is included in two NDAs.

This patent has four hundred and ninety-one patent family members in fourteen countries.

Summary for Patent: 7,101,993

Title:Oligonucleotides containing 2'-O-modified purines
Abstract: Compounds are provided containing purine nucleotides that bear moieties X at the 2' position thereof wherein X is R.sub.1--(R.sub.2).sub.n; R.sub.1 is C.sub.3-C.sub.20 alkyl, C.sub.4-C.sub.20 alkenyl or C.sub.2-C.sub.20 alkynyl; R.sub.2 is halogen, hydroxyl, thiol, keto, carboxyl, nitro, nitroso, nitrile, trifluoromethyl, trifluoromethoxy, O-alkyl, S-alkyl, NH-alkyl, N-dialkyl, O-aryl, S-aryl, NH-aryl, O-aralkyl, S-aralkyl, NH-aralkyl, amino, N-phthalimido, imidazole, azido, hydrazino, hydroxylamino, isocyanato, sulfoxide, sulfone, sulfide, disulfide, silyl, aryl, heterocycle, carbocycle, intercalator, reporter molecule, conjugate, polyamine, polyamide, polyalkylene glycol, polyether, a group that enhances the pharmacodynamic properties of oligonucleotides, or a group that enhances the pharmacokinetic properties of oligonucleotides; and n is an integer from 0 to about 6. Such compounds are useful for modulating the synthesis of proteins.
Inventor(s): Cook; Phillip Dan (San Marcos, CA), McGee; Daniel Peter Claude (Boulder, CA), Guinosso; Charles John (Visia, CA)
Assignee: ISIS Pharmaceuticals, Inc. (Carlsbad, CA)
Application Number:07/967,267
Patent Claim Types:
see list of patent claims

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Patent Submitted Product Substance Delist Req. Patented / Exclusive Use
Biogen IdecSPINRAZAnusinersen sodiumSOLUTION;INTRATHECAL209531-001Dec 23, 2016RXYesYes► Subscribe► Subscribe► SubscribeY
Kastle Theraps LlcKYNAMROmipomersen sodiumSOLUTION;SUBCUTANEOUS203568-001Jan 29, 2013RXYesYes► Subscribe► Subscribe► SubscribeY
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International Patent Family for Patent: 7,101,993

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria154947► Subscribe
Austria159025► Subscribe
Austria160353► Subscribe
Austria168561► Subscribe
Austria186072► Subscribe
Austria187771► Subscribe
Austria191933► Subscribe
Austria196321► Subscribe
Austria204879► Subscribe
Austria212063► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Argus Health
Boehringer Ingelheim
Federal Trade Commission

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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