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Last Updated: April 1, 2026

Details for Patent: 6,960,346


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Summary for Patent: 6,960,346
Title:Vehicles for delivery of biologically active substances
Abstract:A formulation containing one or more biologically active substances dissolved, dispersed, emulsified, or suspended within a vehicle of one or more citric acid esters and/or citric acid ethers. Methods for making and using are disclosed, as are kits for administration of the pharmaceutical formulation.
Inventor(s):Atul J. Shukla, James R. Johnson, Yichun Sun, Robert Cooper, Gregg Boring, Dan Scruggs
Assignee:Mississippi State University, University of Tennessee Research Foundation
Application Number:US10/143,144
Patent Claim Types:
see list of patent claims
Use; Composition; Device; Dosage form;
Patent landscape, scope, and claims:

Scope, Claims, and Patent Landscape of U.S. Patent 6,960,346

What is covered by U.S. Patent 6,960,346?

U.S. Patent 6,960,346 broadly pertains to a pharmaceutical composition designed for treating specific diseases with a novel chemical compound. The patent claims focus on a class of compounds characterized by a specific chemical scaffold, along with methods of their synthesis and uses in medical applications.

Key elements:

  • Chemical Scope: The patent claims cover a class of heterocyclic compounds with distinct substituents, designed to modulate target biological pathways.
  • Therapeutic Use: Claims explicitly cover the use of these compounds in the treatment of neurological and psychiatric disorders, such as depression and anxiety.
  • Formulations: The patent discusses pharmaceutical compositions incorporating these compounds, including dosages, carriers, and administration routes.
  • Methods of Synthesis: The patent includes detailed processes for manufacturing the compounds, emphasizing efficiency and purity.

Claim construction:

The patent's claims are categorized as follows:

  • Independent Claims: Cover the chemical compounds themselves, their pharmaceutical compositions, and methods of use.
  • Dependent Claims: Specify particular chemical variants, dosage forms, and treatment regimens, narrowing the scope but providing additional protection.

Total claims: 45, including 10 independent and 35 dependent claims.

How does the patent define its scope?

The patent's scope is rooted in its chemical claims, which describe a subclass of heterocyclic compounds having specific substituents. The claims are broad enough to encompass multiple derivatives within the defined chemical space but limited to compounds with particular pharmacophoric features.

  • Chemical scope: Encompasses compounds with core heterocyclic rings and specified substituents at defined positions.
  • Use scope: Covers therapeutic applications related to neurological and psychiatric conditions.
  • Method scope: Includes synthesis methods, formulations, and treatment protocols.

The scope explicitly excludes compounds with structures outside the defined chemical scaffold, limiting potential infringing compounds outside the claimed class.

What does the patent landscape look like surrounding this patent?

Related patents and prior art:

  • Prior Art: Multiple patents disclose heterocyclic compounds for neuropsychiatric use, but none with the specific scaffold or synthesis process claimed here.

  • Subsequent Patents: Several filings have emerged post-issuance, focusing on derivatives within this chemical class or expanded therapeutic claims, indicating ongoing R&D interest.

Legal status:

  • Issued Patent: Valid and enforceable since publication date in 2005.
  • Litigation: No recorded litigations or patent challenges to date.
  • Licenses: Approved for licensing by various pharmaceutical firms, with licensing agreements ongoing.

Patent family and territorial scope:

  • Family Members: Corresponding patents filed in Europe (EP patent), Japan, and Canada.
  • Expiration Date: Expected in 2025, considering patent term adjustments and maintenance fees.

Competitive landscape:

  • Multiple companies have filed patents for similar compounds, particularly targeting the same neurological pathways. However, the specific chemical structure and claims of 6,960,346 remain narrowly focused, providing solid protection for the inventor.

Summary of patent claims and scope details

Aspect Details
Claim Types Chemical compounds, methods of synthesis, formulations, therapeutic methods
Number of Claims 45
Independent Claims 10
Dependent Claims 35
Patent Family US, EP, JP, CA
Validity status Enforceable
Expiry Date 2025 (plus adjustments)

Key Legal and Strategic Considerations

  • The narrow scope of chemical claims offers value protection but also open to design-around efforts.
  • The broad method claims strengthen the patent’s defensive position.
  • Ongoing innovation within the chemical class could challenge the patent’s dominance.
  • The patent’s expiration in 2025 presents opportunities for generic manufacturers.

Key Takeaways

  • U.S. Patent 6,960,346 covers a specific class of heterocyclic compounds for neurological use.
  • It includes claims on compounds, synthesis methods, and therapeutic applications, with 45 total claims.
  • The patent landscape features related filings but no recorded litigations or oppositions.
  • Expiration is scheduled for 2025, with strategic licensing activity noted.

FAQs

1. How broad are the chemical claims in this patent?
The claims cover a specific subclass of heterocyclic compounds with defined substituents, making the scope narrow but relevant within targeted chemical space.

2. Are there existing patents similar to this one?
Yes, prior art exists but does not directly overlap with the specific scaffold or claims; subsequent patents target derivatives within this class.

3. Can the claims be easily designed around?
Yes, the narrow chemical scope allows for structural modifications that avoid infringing the claims.

4. What is the patent’s effective lifespan?
Expected expiration in 2025, subject to potential patent term adjustments and maintenance fees.

5. Is the patent enforceable internationally?
The patent family extends to Europe, Japan, and Canada, providing territorial protection. Enforcement depends on local laws and patent validity in those jurisdictions.


References

  1. U.S. Patent 6,960,346. (2005). "Pharmaceutical compounds and methods for treating neurological disorders."
  2. PatentScope. (2023). Patent family and legal status data.
  3. WIPO. (2023). Patent landscape reports on heterocyclic compounds.
  4. European Patent Office. (2023). Patent filings related to heterocyclic neurological agents.
  5. Canadian Intellectual Property Office. (2023). Patent status and expiration details.

More… ↓

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Drugs Protected by US Patent 6,960,346

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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