Details for Patent: 6,949,527
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Summary for Patent: 6,949,527
Title: | 6-Mercapto-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block |
Abstract: | Disclosed is a 6-mercapto-cyclodextrin derivative having a general formula (I, ) wherein m is 0-7 and n is 1-8 and m+n=7 or 8; R is (C.sub.1-6) alkylene, optionally substituted with 1-3 OH groups, or (CH.sub.2).sub.o -phenylene-CH.sub.2).sub.p --; o and p are independently 0-4; X is COOH, CONHR.sub.3, NHCOR.sub.2, SO.sub.2 OH, PO(OH).sub.2, O(CH.sub.2 --CH.sub.2 --O).sub.q --H, OH or tetrazol-5-yl: R.sub.2 is H or (C.sub.1-3)alkyl; R.sub.2 is carboxyphenyl; q is 1-3; or pharmaceutically acceptable salts thereof. The 6-mercaptocyclodextrin derivative is highly suitable for use in the reversal of drug-induced neuromuscular block. |
Inventor(s): | Zhang; Mingqiang (Montreal, CA), Palin; Ronald (Near Kilsyth, GB), Bennett; David Jonathan (Edinburgh, GB) |
Assignee: | Akzo Nobel N.V. (Arnhem, NL) |
Application Number: | 10/603,355 |
Patent Claim Types: see list of patent claims | Compound; Device; Use; |
Drugs Protected by US Patent 6,949,527
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
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>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 6,949,527
Foriegn Application Priority Data | ||
Foreign Country | Foreign Patent Number | Foreign Patent Date |
99309558 | Nov 29, 1999 |
International Family Members for US Patent 6,949,527
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
Argentina | 026605 | ⤷ Try a Trial | |||
Austria | 288450 | ⤷ Try a Trial | |||
Australia | 5438001 | ⤷ Try a Trial | |||
Australia | 776536 | ⤷ Try a Trial | |||
Brazil | 0015947 | ⤷ Try a Trial | |||
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