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Serving hundreds of leading biopharmaceutical companies globally:

QuintilesIMS
Julphar
Baxter
Boehringer Ingelheim
UBS
Federal Trade Commission
Merck
Citi
Mallinckrodt

Generated: May 23, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,949,527

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Which drugs does patent 6,949,527 protect, and when does it expire?

Patent 6,949,527 protects BRIDION and is included in one NDA.

This patent has thirty-nine patent family members in twenty-nine countries.
Summary for Patent: 6,949,527
Title: 6-Mercapto-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block
Abstract:Disclosed is a 6-mercapto-cyclodextrin derivative having a general formula (I, ) wherein m is 0-7 and n is 1-8 and m+n=7 or 8; R is (C.sub.1-6) alkylene, optionally substituted with 1-3 OH groups, or (CH.sub.2).sub.o -phenylene-CH.sub.2).sub.p --; o and p are independently 0-4; X is COOH, CONHR.sub.3, NHCOR.sub.2, SO.sub.2 OH, PO(OH).sub.2, O(CH.sub.2 --CH.sub.2 --O).sub.q --H, OH or tetrazol-5-yl: R.sub.2 is H or (C.sub.1-3)alkyl; R.sub.2 is carboxyphenyl; q is 1-3; or pharmaceutically acceptable salts thereof. The 6-mercaptocyclodextrin derivative is highly suitable for use in the reversal of drug-induced neuromuscular block.
Inventor(s): Zhang; Mingqiang (Montreal, CA), Palin; Ronald (Near Kilsyth, GB), Bennett; David Jonathan (Edinburgh, GB)
Assignee: Akzo Nobel N.V. (Arnhem, NL)
Application Number:10/603,355
Patent Claim Types:
see list of patent claims
Compound; Device; Use;

Drugs Protected by US Patent 6,949,527

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Organon Sub Merck BRIDION sugammadex sodium SOLUTION;INTRAVENOUS 022225-002 Dec 15, 2015 RX Yes No ➤ Try a Free Trial ➤ Try a Free Trial REVERSAL OF NEUROMUSCULAR BLOCKAGE INDUCED BY ROCURONIUM BROMIDE OR VECURONIUM BROMIDE ➤ Try a Free Trial
Organon Sub Merck BRIDION sugammadex sodium SOLUTION;INTRAVENOUS 022225-001 Dec 15, 2015 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial REVERSAL OF NEUROMUSCULAR BLOCKAGE INDUCED BY ROCURONIUM BROMIDE OR VECURONIUM BROMIDE ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 6,949,527

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
99309558Nov 29, 1999

Non-Orange Book US Patents Family Members for Patent 6,949,527

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
6,670,340 6-Mercapto-cyclodextrin derivatives:reversal agents for drug-induced neuromuscular block ➤ Try a Free Trial
RE44733 6-mercapto-cyclodextrin derivatives:reversal agents for drug-induced neuromuscular block ➤ Try a Free Trial
Patent No. Title Estimated Patent Expiration

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International Family Members for US Patent 6,949,527

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 026605 ➤ Try a Free Trial
Austria 288450 ➤ Try a Free Trial
Australia 5438001 ➤ Try a Free Trial
Australia 776536 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Cantor Fitzgerald
Fuji
Federal Trade Commission
Julphar
Express Scripts
Cerilliant
Dow
Fish and Richardson
Merck

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