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Serving hundreds of leading biopharmaceutical companies globally:

Harvard Business School
Chubb
Citi
QuintilesIMS
Julphar
Baxter
Healthtrust
Johnson and Johnson
AstraZeneca

Generated: April 20, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,858,650

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Which drugs does patent 6,858,650 protect, and when does it expire?

Patent 6,858,650 protects TOVIAZ and is included in one NDA.

This patent has sixty-nine patent family members in twenty-nine countries.
Summary for Patent: 6,858,650
Title: Stable salts of novel derivatives of 3,3-diphenylpropylamines
Abstract:The present invention concerns highly pure, crystalline, stable compounds of novel derivatives of 3,3-diphenylpropylamines in the form of their salts, a method for the manufacture and highly pure, stable intermediate products. The method is in particular characterized by regio- and chemoselectivity and high yield. Salts of phenolic monoesters of 3,3-diphenylpropylamines are provided, that are particularly well-suited for use in pharmaceutical formulations. Preferred compounds are R-(+)-2-(3-diisopropylamino-1-phenyl-propyl)-4-hydroxymethylphenylisobutyr ate ester hydrogen fumarate and R-(+)-2-(3-diisopropylamino-1-phenylpropyl)-4-hydroxymethylphenylisobutyra te ester hydrochloride hydrate. Furthermore, stable, crystalline intermediate products that are essential for obtaining the abovementioned salts are provided. A preferred intermediate product is R-(-)-3-(3-diisopropylamino-phenyl-propyl)-4-hydroxy-benzoic acid methyl ester.
Inventor(s): Meese; Claus (Monheim, DE)
Assignee: Schwarz Pharma AG (DE)
Application Number:10/130,214
Patent Claim Types:
see list of patent claims
Compound; Formulation; Use;

Drugs Protected by US Patent 6,858,650

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Pfizer TOVIAZ fesoterodine fumarate TABLET, EXTENDED RELEASE;ORAL 022030-001 Oct 31, 2008 AB RX Yes No ➤ Sign Up ➤ Sign Up Y TREATMENT OF OVERACTIVE BLADDER WITH SYMPTOMS OF URGE URINARY INCONTINENCE, URGENCY, AND FREQUENCY ➤ Sign Up
Pfizer TOVIAZ fesoterodine fumarate TABLET, EXTENDED RELEASE;ORAL 022030-002 Oct 31, 2008 AB RX Yes Yes ➤ Sign Up ➤ Sign Up Y TREATMENT OF OVERACTIVE BLADDER WITH SYMPTOMS OF URGE URINARY INCONTINENCE, URGENCY, AND FREQUENCY ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 6,858,650

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Germany199 55 190Nov 16, 1999
PCT Information
PCT FiledNovember 15, 2000PCT Application Number:PCT/EP00/11309
PCT Publication Date:May 25, 2001PCT Publication Number: WO01/35957

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Serving hundreds of leading biopharmaceutical companies globally:

Chinese Patent Office
Merck
Farmers Insurance
Julphar
Queensland Health
Deloitte
Medtronic
Colorcon
McKinsey

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