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Serving hundreds of leading biopharmaceutical companies globally:

QuintilesIMS
Fish and Richardson
Cantor Fitzgerald
Chinese Patent Office
Healthtrust
Moodys
Citi
Cerilliant
Covington

Generated: April 26, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,852,689

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Summary for Patent: 6,852,689
Title: Methods for administration of antibiotics
Abstract:The invention provides methods for administering a therapeutically effective amount of daptomycin while minimizing skeletal muscle toxicity. The methods provide daptomycin administration at a dosing interval of 24 hours or greater. This long dosing interval minimizes skeletal muscle toxicity and allows for higher peak concentrations of daptomycin, which is related to daptomycin's efficacy. The invention also provides methods of administering lipopeptide antibiotics other than daptomycin while minimizing skeletal muscle toxicity by administering a therapeutically effective amount of the lipopeptide antibiotic at a dosage interval that does not result in muscle toxicity. The invention also provides methods of administering quinupristin/dalfopristin while minimizing skeletal muscle toxicity by administering a therapeutically effective amount of quinupristin/dalfopristin at a dosage interval that dos not result in muscle toxicity.
Inventor(s): Oleson, Jr.; Frederick B. (Concord, MA), Tally; Francis P. (Lincoln, MA)
Assignee: Cubist Pharmaceuticals, Inc. (Lexington, MA)
Application Number:10/082,544
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 6,852,689

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Serving hundreds of leading biopharmaceutical companies globally:

AstraZeneca
Moodys
Chinese Patent Office
Merck
Mallinckrodt
Baxter
Cerilliant
Harvard Business School
Covington

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