Details for Patent: 6,852,689

Summary for Patent: 6,852,689

Title:	Methods for administration of antibiotics
Abstract:	The invention provides methods for administering a therapeutically effective amount of daptomycin while minimizing skeletal muscle toxicity. The methods provide daptomycin administration at a dosing interval of 24 hours or greater. This long dosing interval minimizes skeletal muscle toxicity and allows for higher peak concentrations of daptomycin, which is related to daptomycin's efficacy. The invention also provides methods of administering lipopeptide antibiotics other than daptomycin while minimizing skeletal muscle toxicity by administering a therapeutically effective amount of the lipopeptide antibiotic at a dosage interval that does not result in muscle toxicity. The invention also provides methods of administering quinupristin/dalfopristin while minimizing skeletal muscle toxicity by administering a therapeutically effective amount of quinupristin/dalfopristin at a dosage interval that dos not result in muscle toxicity.
Inventor(s):	Oleson, Jr.; Frederick B. (Concord, MA), Tally; Francis P. (Lincoln, MA)
Assignee:	Cubist Pharmaceuticals, Inc. (Lexington, MA)
Application Number:	10/082,544
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 6,852,689
Patent Claim Types: see list of patent claims	Use;

Drugs Protected by US Patent 6,852,689

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate

International Family Members for US Patent 6,852,689

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Austria	322280
Australia	6268799
Australia	764348