Last Updated: November 8, 2026

Details for Patent: 6,838,464

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Summary for Patent: 6,838,464
Title:2,4-Di(hetero-)arylamino(-oxy)-5-substituted pyrimidines as antineaoplastic agents
Abstract:Pyrimidine derivatives of formula (I) wherein Q1, Q2, G and R1 are as defined within; and pharmaceutically acceptable salts and in vivo hydrolysable esters thereof are described. Processes for their manufacture, pharmaceutical compositions and their use as cyclin-dependent serine/threonine kinase (CDK) and focal adhesion kinase (FAK) inhibitors are also described.
Inventor(s):Elizabeth Janet Pease, Emma Jane Williams, Robert Hugh Bradbury, Stuart Eric Pearson
Assignee: AstraZeneca AB
Application Number:US10/203,025
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 6,838,464
Patent Claim Types:
see list of patent claims
Use; Composition; Process;

Drugs Protected by US Patent 6,838,464

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 6,838,464

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom0004887Mar 01, 2000
PCT Information
PCT FiledFebruary 26, 2001PCT Application Number:PCT/GB01/00829
PCT Publication Date:September 07, 2001PCT Publication Number: WO01/64656

International Family Members for US Patent 6,838,464

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 472537 ⤷  Start Trial
Australia 2001233979 ⤷  Start Trial
Australia 3397901 ⤷  Start Trial
Brazil 0108879 ⤷  Start Trial
Brazil 122014024864 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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