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Last Updated: November 22, 2019

DrugPatentWatch Database Preview

Details for Patent: 6,762,180

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Which drugs does patent 6,762,180 protect, and when does it expire?

Patent 6,762,180 protects OFEV and is included in one NDA.

This patent has sixty patent family members in forty-two countries.

Summary for Patent: 6,762,180
Title: Substituted indolines which inhibit receptor tyrosine kinases
Abstract:Indolinones of the formula ##STR1## having an inhibitory effect on receptor tyrosine kinases and cyclin/CDK complexes, as well as on the proliferation of endothelial cells and various tumor cells. Exemplary are: (a) 3-Z-[1-(4-(piperidin-1-yl-methyl)-anilino)-1-phenyl-methylene]-6-ethoxycar bonyl-2-indolinone, (b) 3-Z-[(1-(4-(piperidin-1-yl-methyl)-anilino)-1-phenyl-methylene]-6-carbamoy l-2-indolinone, and (c) 3-Z-[1-(4-(piperidin-1-yl-methyl)-anilino)-1-phenyl-methylene]-6-metboxyca rbonyl-2-indolinone.
Inventor(s): Roth; Gerald Juergen (Biberach, DE), Heckel; Armin (Biberach, DE), Walter; Rainer (Biberach, DE), Van Meel; Jacobus (Moedling, AT), Redemann; Norbert (Biberach, DE), Tontsch-Grunt; Ulrike (Baden, AT), Spevak; Walter (Oberrohrbach, AT), Hilberg; Frank (Vienna, AT)
Assignee: Boehringer Ingelheim Pharma KG (Ingelheim, DE)
Application Number:09/678,682
Patent Claim Types:
see list of patent claims
Compound; Composition;

Drugs Protected by US Patent 6,762,180

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Boehringer Ingelheim OFEV nintedanib esylate CAPSULE;ORAL 205832-001 Oct 15, 2014 RX Yes No   Start Trial   Start Trial Y Y   Start Trial
Boehringer Ingelheim OFEV nintedanib esylate CAPSULE;ORAL 205832-002 Oct 15, 2014 RX Yes Yes   Start Trial   Start Trial Y Y   Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 6,762,180

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Germany199 49 208Oct 13, 1999
Germany100 42 696Aug 31, 2000

International Family Members for US Patent 6,762,180

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 026036   Start Trial
Austria 439342   Start Trial
Australia 1023301   Start Trial
Australia 781939   Start Trial
Bulgaria 106587   Start Trial
Bulgaria 65983   Start Trial
Brazil 0014735   Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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Serving leading biopharmaceutical companies globally:

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Express Scripts
Dow
Boehringer Ingelheim

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