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Serving leading biopharmaceutical companies globally:

Dow
Moodys
Deloitte
QuintilesIMS
Fuji
Johnson and Johnson
Mallinckrodt
Cantor Fitzgerald
Boehringer Ingelheim
UBS

Generated: February 20, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,699,833

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Summary for Patent: 6,699,833
Title: Pharmaceutical formulations for sustained drug delivery
Abstract:Sustained delivery formulations comprising a water-insoluble complex of a peptide and a carrier macromolecule are disclosed. The formulations of the invention allow for loading of high concentrations of peptide in a small volume and for delivery of a pharmaceutically active peptide for prolonged periods, e.g., one month, after administration of the complex. The complexes of the invention can be milled or crushed to a fine powder. In powdered form, the complexes form stable aqueous suspensions and dispersions, suitable for injection. In a preferred embodiment, the peptide of the complex is an LHRH analogue, preferably an LHRH antagonist, and the carrier macromolecule is an anionic polymer, preferably carboxymethylcellulose. Methods of making the complexes of the invention, and methods of using LHRH-analogue-containing complexes to treat conditions treatable with an LHRH analogue, are also disclosed.
Inventor(s): Gefter; Malcolm L. (Lincoln, MA), Barker; Nicholas (Southborough, MA), Musso; Gary (Hopkinton, MA), Molineaux; Christopher J. (Brookline, CA)
Assignee: Praecis Pharmaceuticals, Inc. (Cambridge, MA)
Application Number:09/349,914
Patent Claim Types:
see list of patent claims
Composition; Delivery;

Drugs Protected by US Patent 6,699,833

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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International Patents Family Members for US Patent 6,699,833

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Ukraine 68343 ➤ Try a Free Trial
Turkey 9901382 ➤ Try a Free Trial
Tunisia SN97205 ➤ Try a Free Trial
Slovakia 287305 ➤ Try a Free Trial
Slovakia 79399 ➤ Try a Free Trial
Slovenia 0952843 ➤ Try a Free Trial
Russian Federation 2202371 ➤ Try a Free Trial
Portugal 952843 ➤ Try a Free Trial
Poland 200675 ➤ Try a Free Trial
Poland 334076 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

UBS
Moodys
McKinsey
Merck
Boehringer Ingelheim
Daiichi Sankyo
Harvard Business School
Cipla
Covington

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