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Serving hundreds of leading biopharmaceutical companies globally:

Boehringer Ingelheim
Farmers Insurance
Accenture
Cipla
Chubb
Teva
Mallinckrodt
Federal Trade Commission
Covington

Generated: April 22, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,699,833

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Summary for Patent: 6,699,833
Title: Pharmaceutical formulations for sustained drug delivery
Abstract:Sustained delivery formulations comprising a water-insoluble complex of a peptide and a carrier macromolecule are disclosed. The formulations of the invention allow for loading of high concentrations of peptide in a small volume and for delivery of a pharmaceutically active peptide for prolonged periods, e.g., one month, after administration of the complex. The complexes of the invention can be milled or crushed to a fine powder. In powdered form, the complexes form stable aqueous suspensions and dispersions, suitable for injection. In a preferred embodiment, the peptide of the complex is an LHRH analogue, preferably an LHRH antagonist, and the carrier macromolecule is an anionic polymer, preferably carboxymethylcellulose. Methods of making the complexes of the invention, and methods of using LHRH-analogue-containing complexes to treat conditions treatable with an LHRH analogue, are also disclosed.
Inventor(s): Gefter; Malcolm L. (Lincoln, MA), Barker; Nicholas (Southborough, MA), Musso; Gary (Hopkinton, MA), Molineaux; Christopher J. (Brookline, CA)
Assignee: Praecis Pharmaceuticals, Inc. (Cambridge, MA)
Application Number:09/349,914
Patent Claim Types:
see list of patent claims
Composition; Delivery;

Drugs Protected by US Patent 6,699,833

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Serving hundreds of leading biopharmaceutical companies globally:

QuintilesIMS
Citi
Cerilliant
Queensland Health
Argus Health
Boehringer Ingelheim
Cipla
Covington
Fish and Richardson

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