Details for Patent: 6,589,955
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Summary for Patent: 6,589,955
Title: | Pediatric formulation of gatifloxacin |
Abstract: | There is provided in accordance with the present invention the quinolone antibacterial gatifloxacin adequately taste-masked so that it can be utilized for pediatric formulations. A crystalline co-precipitate of gatifloxacin and one or both of stearic acid and palmitic acid in a narrow weight ratio has been found to effectively mask the bitter taste of gatifloxacin. The taste of gatifloxacin is effectively masked in the mouth and in aqueous suspension through a full dosage cycle, typically fourteen days. Gatifloxacin in the subject crystalline co-precipitates has been found to be readily available for absorption from the stomach. |
Inventor(s): | Raghavan; Krishnaswamy S. (Cranbury, NJ), Ranadive; Sunanda A. (East Brunswick, NJ), Bembenek; Kenneth S. (Dayton, NJ), Benkerrour; Loutfy (Paris, FR), Trognon; Veronique (La Turballe, FR), Corrao; Richard G. (Jackson, NJ), Esposito; Luigi (Howell, NJ) |
Assignee: | Bristol-Myers Squibb Company (Princeton, NJ) |
Application Number: | 10/143,487 |
Patent Claim Types: see list of patent claims | Compound; Composition; Dosage form; Use; Process; |
Drugs Protected by US Patent 6,589,955
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International Family Members for US Patent 6,589,955
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Argentina | 034483 | ⤷ Try a Trial | |||
Australia | 2002345534 | ⤷ Try a Trial | |||
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Brazil | 0209692 | ⤷ Try a Trial | |||
Canada | 2450742 | ⤷ Try a Trial | |||
China | 1264514 | ⤷ Try a Trial | |||
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