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Generated: September 22, 2017

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Title: Pediatric formulation of gatifloxacin
Abstract:There is provided in accordance with the present invention the quinolone antibacterial gatifloxacin adequately taste-masked so that it can be utilized for pediatric formulations. A crystalline co-precipitate of gatifloxacin and one or both of stearic acid and palmitic acid in a narrow weight ratio has been found to effectively mask the bitter taste of gatifloxacin. The taste of gatifloxacin is effectively masked in the mouth and in aqueous suspension through a full dosage cycle, typically fourteen days. Gatifloxacin in the subject crystalline co-precipitates has been found to be readily available for absorption from the stomach.
Inventor(s): Raghavan; Krishnaswamy S. (Cranbury, NJ), Ranadive; Sunanda A. (East Brunswick, NJ), Bembenek; Kenneth S. (Dayton, NJ), Benkerrour; Loutfy (Paris, FR), Trognon; Veronique (La Turballe, FR), Corrao; Richard G. (Jackson, NJ), Esposito; Luigi (Howell, NJ)
Assignee: Bristol-Myers Squibb Company (Princeton, NJ)
Application Number:10/143,487
Patent Claim Types:
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Compound; Composition; Dosage form; Use; Process;

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International Patent Family for Patent: ► Subscribe

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Slovakia14152003► Subscribe
Russian Federation2288218► Subscribe
Russian Federation2003136068► Subscribe
Poland366559► Subscribe
Peru01262003► Subscribe
New Zealand529611► Subscribe
Norway20035605► Subscribe
MexicoPA03011451► Subscribe
South Korea100888519► Subscribe
South Korea20040011543► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving 500+ biopharmaceutical companies globally:

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