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Serving leading biopharmaceutical companies globally:

Cantor Fitzgerald
Medtronic
US Army
QuintilesIMS
Covington
Julphar
Boehringer Ingelheim
Cipla
Fish and Richardson
US Department of Justice

Generated: February 20, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,582,728

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Summary for Patent: 6,582,728
Title: Spray drying of macromolecules to produce inhaleable dry powders
Abstract:According to the subject invention, dispersible dry powder pharmaceutical-based compositions are provided, including methods for their manufacture and dry powder dispersion devices. A dispersible dry powder pharmaceutical-based composition is one having a moisture content of less than about 10% by weight (%w) water, usually below about 5%w and preferably less than about 3%w; a particle size of about 1.0-5.0 .mu.m mass median diameter (MMD), usually 1.0-4.0 .mu.m MMD, and preferably 1.0-3.0 .mu.m MMD; a delivered dose of about >30%, usually >40%, preferably >50%, and most preferred >60%; and an aerosol particle size distribution of about 1.0-5.0 .mu.m mass median aerodynamic diameter (MMAD), usually 1.5-4.5 .mu.m MMAD, and preferably 1.5-4.0 MMAD. Such composition are of pharmaceutical grade purity.
Inventor(s): Platz; Robert M. (Half Moon Bay, CA), Patton; John S. (San Carlos, CA), Foster; Linda (Sunnyvale, CA), Eljamal; Mohammed (San Jose, CA)
Assignee: Inhale Therapeutic Systems, Inc. (San Carlos, CA)
Application Number:08/423,515
Patent Claim Types:
see list of patent claims
Use; Composition; Formulation; Process;

Drugs Protected by US Patent 6,582,728

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Pfizer EXUBERA insulin recombinant human POWDER;INHALATION 021868-001 Jan 27, 2006 DISCN No No ➤ Try a Free Trial ➤ Try a Free Trial Y ➤ Try a Free Trial
Pfizer EXUBERA insulin recombinant human POWDER;INHALATION 021868-002 Jan 27, 2006 DISCN No No ➤ Try a Free Trial ➤ Try a Free Trial Y ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 6,582,728

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
6,514,496 Dispersible antibody compositions and methods for their preparation and use ➤ Try a Free Trial
6,089,228 Apparatus and methods for dispersing dry powder medicaments ➤ Try a Free Trial
6,231,851 Methods and compositions for the dry powder formulation of interferons ➤ Try a Free Trial
5,458,135 Method and device for delivering aerosolized medicaments ➤ Try a Free Trial
7,138,141 Dispersible macromolecule compositions and methods for their preparation and use ➤ Try a Free Trial
5,775,320 Method and device for delivering aerosolized medicaments ➤ Try a Free Trial
5,994,314 Compositions and methods for nucleic acid delivery to the lung ➤ Try a Free Trial
6,372,258 Methods of spray-drying a drug and a hydrophobic amino acid ➤ Try a Free Trial
6,797,258 Compositions and methods for the pulmonary delivery of aerosolized macromolecules ➤ Try a Free Trial
6,258,341 Stable glassy state powder formulations ➤ Try a Free Trial
Patent No. Title Estimated Patent Expiration

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International Patents Family Members for US Patent 6,582,728

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 0846009 ➤ Try a Free Trial
Spain 2316917 ➤ Try a Free Trial
Greece 3032973 ➤ Try a Free Trial
Georgia, Republic of P20032985 ➤ Try a Free Trial
Georgia, Republic of P20012345 ➤ Try a Free Trial
Finland 971173 ➤ Try a Free Trial
Finland 116195 ➤ Try a Free Trial
Finland 963468 ➤ Try a Free Trial
Finland 112917 ➤ Try a Free Trial
Finland 951465 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Accenture
Argus Health
Farmers Insurance
QuintilesIMS
Fish and Richardson
Cantor Fitzgerald
Cerilliant
Merck
Healthtrust

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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