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Serving hundreds of leading biopharmaceutical companies globally:

Chinese Patent Office
AstraZeneca
Cantor Fitzgerald
Fish and Richardson
Healthtrust
Farmers Insurance
Federal Trade Commission
US Department of Justice
Covington

Generated: June 23, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,582,728

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Summary for Patent: 6,582,728
Title: Spray drying of macromolecules to produce inhaleable dry powders
Abstract:According to the subject invention, dispersible dry powder pharmaceutical-based compositions are provided, including methods for their manufacture and dry powder dispersion devices. A dispersible dry powder pharmaceutical-based composition is one having a moisture content of less than about 10% by weight (%w) water, usually below about 5%w and preferably less than about 3%w; a particle size of about 1.0-5.0 .mu.m mass median diameter (MMD), usually 1.0-4.0 .mu.m MMD, and preferably 1.0-3.0 .mu.m MMD; a delivered dose of about >30%, usually >40%, preferably >50%, and most preferred >60%; and an aerosol particle size distribution of about 1.0-5.0 .mu.m mass median aerodynamic diameter (MMAD), usually 1.5-4.5 .mu.m MMAD, and preferably 1.5-4.0 MMAD. Such composition are of pharmaceutical grade purity.
Inventor(s): Platz; Robert M. (Half Moon Bay, CA), Patton; John S. (San Carlos, CA), Foster; Linda (Sunnyvale, CA), Eljamal; Mohammed (San Jose, CA)
Assignee: Inhale Therapeutic Systems, Inc. (San Carlos, CA)
Application Number:08/423,515
Patent Claim Types:
see list of patent claims
Use; Composition; Formulation; Process;

Drugs Protected by US Patent 6,582,728

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Pfizer EXUBERA insulin recombinant human POWDER;INHALATION 021868-001 Jan 27, 2006 DISCN No No ➤ Sign Up ➤ Sign Up Y ➤ Sign Up
Pfizer EXUBERA insulin recombinant human POWDER;INHALATION 021868-002 Jan 27, 2006 DISCN No No ➤ Sign Up ➤ Sign Up Y ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 6,582,728

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
5,775,320 Method and device for delivering aerosolized medicaments ➤ Sign Up
6,372,258 Methods of spray-drying a drug and a hydrophobic amino acid ➤ Sign Up
6,309,671 Stable glassy state powder formulations ➤ Sign Up
6,423,344 Dispersible macromolecule compositions and methods for their preparation and use ➤ Sign Up
Patent No. Title Estimated Patent Expiration

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International Family Members for US Patent 6,582,728

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
African Regional IP Organization (ARIPO) 9801369 ➤ Sign Up
African Regional IP Organization (ARIPO) 987 ➤ Sign Up
Argentina 013854 ➤ Sign Up
Argentina 042921 ➤ Sign Up
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Baxter
Queensland Health
UBS
Julphar
Cerilliant
Express Scripts
Cantor Fitzgerald
AstraZeneca
Daiichi Sankyo

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