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Serving leading biopharmaceutical companies globally:

Baxter
Cerilliant
UBS
Fish and Richardson
Harvard Business School
Covington
Healthtrust
Colorcon
Deloitte
Chubb

Generated: October 17, 2017

DrugPatentWatch Database Preview

Details for Patent: 6,569,837

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Which drugs does patent 6,569,837 protect, and when does it expire?


Patent 6,569,837 protects TYZEKA and is included in two NDAs.

This patent has forty-four patent family members in twenty countries.

Summary for Patent: 6,569,837

Title: .beta.-L-2'-deoxy pyrimidine nucleosides for the treatment of hepatitis B
Abstract:This invention is directed to a method for treating a host infected with hepatitis B comprising administering an effective amount of an anti-HBV biologically active 2'-deoxy-.beta.-L-erythro-pentofuranonucleoside or a pharmaceutically acceptable salt or prodrug thereof, wherein the 2'-deoxy-.beta.-L-erythro-pentofuranonucleoside has the formula: ##STR1## wherein R is selected from the group consisting of H, straight chained, branched or cyclic alkyl, CO-alkyl, CO-aryl, CO-alkoxyalkyl, CO-aryloxyalkyl, CO-substituted aryl, alkylsulfonyl, arylsulfonyl, aralkylsulfonyl, amino acid residue, mono, di, or triphosphate, or a phosphate derivative; and BASE is a purine or pyrimidine base which may be optionally substituted. The 2'-deoxy-.beta.-L-erythro-pentofuranonucleoside or a pharmaceutically acceptable salt or prodrug thereof may be administered either alone or in combination with another 2'-deoxy-.beta.-L-erythro-pentofuranonucleoside or in combination with another anti-hepatitis B agent.
Inventor(s): Gosselin; Gilles (Montpellier, FR), Imbach; Jean-Louis (Montpellier, FR), Bryant; Martin L. (Carlisle, MA)
Assignee: Idenix Pharmaceuticals Inc. (Cambridge, MA)
Application Number:10/022,276
Patent Claim Types:
see list of patent claims
Use; Compound; Composition; Delivery; Dosage form;

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Novartis
TYZEKA
telbivudine
TABLET;ORAL022011-001Oct 25, 2006RXYesYes► Subscribe► Subscribe TREATMENT OF CHRONIC HEPATITIS B IN ADULT PATIENTS
Novartis
TYZEKA
telbivudine
TABLET;ORAL022011-001Oct 25, 2006RXYesYes► Subscribe► Subscribe TREATMENT OF CHRONIC HEPATITIS B IN ADULT PATIENTS WITH EVIDENCE OF VIRAL REPLICATION AND EITHER EVIDENCE OF PERSISTANT ELEVATIONS IN SERUM AMINOTRANSFERASES (ALT OR AST) OR HISTOLOGICALLY ACTIVE DISEASE
Novartis
TYZEKA
telbivudine
SOLUTION;ORAL022154-001Apr 28, 2009DISCNNoNo► Subscribe► Subscribe TREATMENT OF CHRONIC HEPATITIS B IN ADULT PATIENTS
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Non-Orange Book Patents for Patent: 6,569,837

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
6,946,450 .beta.-L-2'-deoxy-nucleosides for the treatment of hepatitis B► Subscribe
2,011,195,922► Subscribe
9,290,533.beta.-L-2'-deoxy-nucleosides for the treatment of hepatitis B► Subscribe
6,444,652 .beta.-L-2'-deoxy-nucleosides for the treatment of hepatitis B► Subscribe
6,566,344 .beta.-L-2'-deoxy-nucleosides for the treatment of hepatitis B► Subscribe
7,304,043.beta.-L-2'-deoxy-nucleosides for the treatment of hepatitis B► Subscribe
6,395,716 .beta.-L-2'-deoxy-nucleosides for the treatment of hepatitis B► Subscribe
7,795,238.beta.-L-2'-deoxy-nucleosides for the treatment of hepatitis B► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Because of the complexity of determining patent expiration dates it is advisable to have patent counsel verify freedom to operate.

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International Patent Family for Patent: 6,569,837

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Cyprus1116988► Subscribe
Cyprus1117836► Subscribe
Brazil9912896► Subscribe
BrazilPI9912896► Subscribe
Canada2340156► Subscribe
China101120947► Subscribe
Canada2599597► Subscribe
China1320128► Subscribe
China1257912► Subscribe
China1478483► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Fuji
QuintilesIMS
Fish and Richardson
McKesson
Farmers Insurance
Moodys
Queensland Health
Colorcon
Dow
Teva

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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