Last Updated: August 9, 2026

Details for Patent: 6,492,365

Name: Drug Patent Intelligence for US Patent 6492365
Creator: DrugPatentWatch
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Summary for Patent: 6,492,365

Title:	Microsomal triglyceride transfer protein
Abstract:	Nucleic acid sequences, particularly DNA sequences, coding for all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, expression vectors containing the DNA sequences, host cells containing the expression vectors, and methods utilizing these materials. The invention also concerns polypeptide molecules comprising all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, and methods for producing these polypeptide molecules. The invention additionally concerns novel methods for preventing, stabilizing or causing regression of atherosclerosis and therapeutic agents having such activity. The invention concerns further novel methods for lowering serum liquid levels and therapeutic agents having such activity.
Inventor(s):	II John R. Wetterau, Daru Young Sharp, Richard E. Gregg
Assignee:	University of Pennsylvania Penn
Application Number:	US08/486,929
Patent Claim Types: see list of patent claims	Use;

Drugs Protected by US Patent 6,492,365

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

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Argentina	001795	⤷ Start Trial
Austria	219514	⤷ Start Trial
Austria	283851	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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