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Serving hundreds of leading biopharmaceutical companies globally:

Fuji
Merck
McKinsey
Cerilliant
Colorcon
Express Scripts
Teva
Argus Health
Covington

Generated: April 24, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,492,365

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Which drugs does patent 6,492,365 protect, and when does it expire?

Patent 6,492,365 protects JUXTAPID and is included in one NDA.

This patent has sixty-four patent family members in thirty countries.
Summary for Patent: 6,492,365
Title: Microsomal triglyceride transfer protein
Abstract:Nucleic acid sequences, particularly DNA sequences, coding for all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, expression vectors containing the DNA sequences, host cells containing the expression vectors, and methods utilizing these materials. The invention also concerns polypeptide molecules comprising all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, and methods for producing these polypeptide molecules. The invention additionally concerns novel methods for preventing, stabilizing or causing regression of atherosclerosis and therapeutic agents having such activity. The invention concerns further novel methods for lowering serum liquid levels and therapeutic agents having such activity.
Inventor(s): Wetterau, II; John R. (Langhorne, PA), Sharp; Daru Young (Perrineville, NJ), Gregg; Richard E. (Pennington, NJ)
Assignee: Bristol-Myers Squibb Company (New York, NY)
Application Number:08/486,929
Patent Claim Types:
see list of patent claims
Use; Compound;

Drugs Protected by US Patent 6,492,365

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Aegerion JUXTAPID lomitapide mesylate CAPSULE;ORAL 203858-001 Dec 21, 2012 RX Yes No ➤ Sign Up ➤ Sign Up TREATMENT OF HYPERCHOLESTEROLEMIA BY DECREASING THE AMOUNT OR ACTIVITY OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN IN PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA ➤ Sign Up
Aegerion JUXTAPID lomitapide mesylate CAPSULE;ORAL 203858-002 Dec 21, 2012 RX Yes No ➤ Sign Up ➤ Sign Up TREATMENT OF HYPERCHOLESTEROLEMIA BY DECREASING THE AMOUNT OR ACTIVITY OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN IN PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA ➤ Sign Up
Aegerion JUXTAPID lomitapide mesylate CAPSULE;ORAL 203858-003 Dec 21, 2012 RX Yes No ➤ Sign Up ➤ Sign Up TREATMENT OF HYPERCHOLESTEROLEMIA BY DECREASING THE AMOUNT OR ACTIVITY OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN IN PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA ➤ Sign Up
Aegerion JUXTAPID lomitapide mesylate CAPSULE;ORAL 203858-004 Apr 23, 2015 RX Yes No ➤ Sign Up ➤ Sign Up TREATMENT OF HYPERCHOLESTEROLEMIA BY DECREASING THE AMOUNT OR ACTIVITY OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN IN PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 6,492,365

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
6,066,650 Inhibitors of microsomal triglyceride transfer protein and method ➤ Sign Up
5,739,135 Inhibitors of microsomal triglyceride transfer protein and method ➤ Sign Up
5,789,197 Microsomal triglyceride transfer protein ➤ Sign Up
5,595,872 Nucleic acids encoding microsomal trigyceride transfer protein ➤ Sign Up
Patent No. Title Estimated Patent Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Colorcon
McKinsey
Dow
Daiichi Sankyo
Teva
Queensland Health
Covington
Federal Trade Commission
Cerilliant

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