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Details for Patent: 6,432,452
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Summary for Patent: 6,432,452
| Title: | Anti-cancer compounds |
| Abstract: | This invention relates to a compound or group of compounds present in an active principle derived from plants of the species Euphorbia peplus, Euphorbia hirta and Euphorbia drummondii, and to pharmaceutical compositions comprising these compounds. Extracts from these plants have been found to show selective cytotoxicity against several different cancer cell lines. The compounds are useful in effective treatment of cancers, particularly malignant melanomas and squamous cell carcinomas (SCCs). In a preferred embodiment of the invention, the compound is selected from the group consisting of jatrophanes, pepluanes, paralianes and ingenanes, and pharmaceutically-acceptable salts or esters thereof, and more particularly jatrophanes of Conformation II. |
| Inventor(s): | Aylward; James Harrison (St. Lucia, AU) |
| Assignee: | Peplin Biotech Pty. Ltd. (Fortitude Valley, AU) |
| Application Number: | 09/486,199 |
| Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for patent 6,432,452 |
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Patent Claim Types: see list of patent claims | Use; Process; |
Drugs Protected by US Patent 6,432,452
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 6,432,452
| Foriegn Application Priority Data | ||
| Foreign Country | Foreign Patent Number | Foreign Patent Date |
| Australia | PO 8640 | Aug 19, 1997 |
| PCT Information | |||
| PCT Filed | August 19, 1998 | PCT Application Number: | PCT/AU98/00656 |
| PCT Publication Date: | February 25, 1999 | PCT Publication Number: | WO99/08994 |
International Family Members for US Patent 6,432,452
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| Austria | 397580 | Start Trial | |||
| Australia | 736230 | Start Trial | |||
| Australia | 8721798 | Start Trial | |||
| Australia | PO864097 | Start Trial | |||
| Brazil | 9811327 | Start Trial | |||
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
