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Generated: October 22, 2017
Which drugs does patent 6,432,452 protect, and when does it expire?
| Title: | Anti-cancer compounds |
| Abstract: | This invention relates to a compound or group of compounds present in an active principle derived from plants of the species Euphorbia peplus, Euphorbia hirta and Euphorbia drummondii, and to pharmaceutical compositions comprising these compounds. Extracts from these plants have been found to show selective cytotoxicity against several different cancer cell lines. The compounds are useful in effective treatment of cancers, particularly malignant melanomas and squamous cell carcinomas (SCCs). In a preferred embodiment of the invention, the compound is selected from the group consisting of jatrophanes, pepluanes, paralianes and ingenanes, and pharmaceutically-acceptable salts or esters thereof, and more particularly jatrophanes of Conformation II. |
| Inventor(s): | Aylward; James Harrison (St. Lucia, AU) |
| Assignee: | Peplin Biotech Pty. Ltd. (Fortitude Valley, AU) |
| Application Number: | 09/486,199 |
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Patent Claim Types: see list of patent claims | Use; Process; |
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leo Labs | PICATO | ingenol mebutate | GEL;TOPICAL | 202833-001 | Jan 23, 2012 | RX | Yes | Yes | ► Subscribe | ► Subscribe | TREATMENT OF ACTINIC KERATOSIS | ||||
Leo Labs | PICATO | ingenol mebutate | GEL;TOPICAL | 202833-002 | Jan 23, 2012 | RX | Yes | Yes | ► Subscribe | ► Subscribe | TREATMENT OF ACTINIC KERATOSIS | ||||
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| Foriegn Application Priority Data | ||
| Foreign Country | Foreign Patent Number | Foreign Patent Date |
| Australia | PO 8640 | Aug 19, 1997 |
| PCT Information | |||
| PCT Filed | August 19, 1998 | PCT Application Number: | PCT/AU98/00656 |
| PCT Publication Date: | February 25, 1999 | PCT Publication Number: | WO99/08994 |
For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.
The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.
| Patent No. | Title | Estimated Patent Expiration | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 6,787,161 | Anti-cancer compounds | ► Subscribe | |||||||||||||
| 7,410,656 | Anti-cancer compounds | ► Subscribe | |||||||||||||
| 6,844,013 | Methods of stimulating the immune system | ► Subscribe | |||||||||||||
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Because of the complexity of determining patent expiration dates it is advisable to have patent counsel verify freedom to operate.
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| Country | Document Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Portugal | 1015413 | ► Subscribe | |||||||||||||
| Luxembourg | 92185 | ► Subscribe | |||||||||||||
| Japan | 2015007130 | ► Subscribe | |||||||||||||
| Japan | 2012031212 | ► Subscribe | |||||||||||||
| Japan | 2001515059 | ► Subscribe | |||||||||||||
| Hungary | 228862 | ► Subscribe | |||||||||||||
| Hungary | 0004262 | ► Subscribe | |||||||||||||
| Spain | 2308810 | ► Subscribe | |||||||||||||
| European Patent Office | 1015413 | ► Subscribe | C300592 | Netherlands | ► Subscribe | ||||||||||
| European Patent Office | 1015413 | ► Subscribe | CA 2013 00024 | Denmark | ► Subscribe | ||||||||||
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws,
it is advisable to have patent counsel verify freedom to operate.
Export unavailable in trial.
Subscribe for complete access.
Serving leading biopharmaceutical companies globally:
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.
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