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Serving hundreds of leading biopharmaceutical companies globally:

Colorcon
Fuji
Chubb
Accenture
QuintilesIMS
Dow
US Department of Justice
US Army
Cerilliant

Generated: April 21, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,432,452

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Which drugs does patent 6,432,452 protect, and when does it expire?

Patent 6,432,452 protects PICATO and is included in one NDA.

This patent has eighteen patent family members in fifteen countries.
Summary for Patent: 6,432,452
Title: Anti-cancer compounds
Abstract:This invention relates to a compound or group of compounds present in an active principle derived from plants of the species Euphorbia peplus, Euphorbia hirta and Euphorbia drummondii, and to pharmaceutical compositions comprising these compounds. Extracts from these plants have been found to show selective cytotoxicity against several different cancer cell lines. The compounds are useful in effective treatment of cancers, particularly malignant melanomas and squamous cell carcinomas (SCCs). In a preferred embodiment of the invention, the compound is selected from the group consisting of jatrophanes, pepluanes, paralianes and ingenanes, and pharmaceutically-acceptable salts or esters thereof, and more particularly jatrophanes of Conformation II.
Inventor(s): Aylward; James Harrison (St. Lucia, AU)
Assignee: Peplin Biotech Pty. Ltd. (Fortitude Valley, AU)
Application Number:09/486,199
Patent Claim Types:
see list of patent claims
Use; Process;

Drugs Protected by US Patent 6,432,452

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Leo Labs PICATO ingenol mebutate GEL;TOPICAL 202833-001 Jan 23, 2012 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial TREATMENT OF ACTINIC KERATOSIS ➤ Try a Free Trial
Leo Labs PICATO ingenol mebutate GEL;TOPICAL 202833-002 Jan 23, 2012 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial TREATMENT OF ACTINIC KERATOSIS ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 6,432,452

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
AustraliaPO 8640Aug 19, 1997
PCT Information
PCT FiledAugust 19, 1998PCT Application Number:PCT/AU98/00656
PCT Publication Date:February 25, 1999PCT Publication Number: WO99/08994

Non-Orange Book US Patents Family Members for Patent 6,432,452

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
7,410,656 Anti-cancer compounds ➤ Try a Free Trial
6,787,161 Anti-cancer compounds ➤ Try a Free Trial
6,844,013 Methods of stimulating the immune system ➤ Try a Free Trial
Patent No. Title Estimated Patent Expiration

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International Patents Family Members for US Patent 6,432,452

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Brazil 9811327 ➤ Try a Free Trial
Canada 2301082 ➤ Try a Free Trial
China 1266421 ➤ Try a Free Trial
Cyprus 1108303 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Julphar
Medtronic
Cantor Fitzgerald
QuintilesIMS
UBS
US Department of Justice
Federal Trade Commission
US Army
Merck

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