Details for Patent: 6,432,452

Summary for Patent: 6,432,452

Title:	Anti-cancer compounds
Abstract:	This invention relates to a compound or group of compounds present in an active principle derived from plants of the species Euphorbia peplus, Euphorbia hirta and Euphorbia drummondii, and to pharmaceutical compositions comprising these compounds. Extracts from these plants have been found to show selective cytotoxicity against several different cancer cell lines. The compounds are useful in effective treatment of cancers, particularly malignant melanomas and squamous cell carcinomas (SCCs). In a preferred embodiment of the invention, the compound is selected from the group consisting of jatrophanes, pepluanes, paralianes and ingenanes, and pharmaceutically-acceptable salts or esters thereof, and more particularly jatrophanes of Conformation II.
Inventor(s):	Aylward; James Harrison (St. Lucia, AU)
Assignee:	Peplin Biotech Pty. Ltd. (Fortitude Valley, AU)
Application Number:	09/486,199
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 6,432,452
Patent Claim Types: see list of patent claims	Use; Process;

Drugs Protected by US Patent 6,432,452

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate

Foreign Priority and PCT Information for Patent: 6,432,452

Foriegn Application Priority Data
Foreign Country	Foreign Patent Number	Foreign Patent Date
Australia	PO 8640	Aug 19, 1997

PCT Information
PCT Filed	August 19, 1998	PCT Application Number:	PCT/AU98/00656
PCT Publication Date:	February 25, 1999	PCT Publication Number:	WO99/08994

International Family Members for US Patent 6,432,452

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Austria	397580
Australia	736230
Australia	8721798