Generated: December 13, 2017
DrugPatentWatch Database Preview
Details for Patent: 6,383,471
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Which drugs does patent 6,383,471 protect, and when does it expire?
Summary for Patent: 6,383,471
|Title:|| Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents|
|Abstract:||The present invention is directed to a pharmaceutical composition including a hydrophobic therapeutic agent having at least one ionizable functional group, and a carrier. The carrier includes an ionizing agent capable of ionizing the functional group, a surfactant, and optionally solubilizers, triglycerides, and neutralizing agents. The invention further relates to a method of preparing such compositions by providing a composition of an ionizable hydrophobic therapeutic agent, an ionizing agent, and a surfactant, and neutralizing a portion of the ionizing agent with a neutralizing agent. The compositions of the invention are particularly suitable for use in oral dosage forms.|
|Inventor(s):|| Chen; Feng-Jing (Salt Lake City, UT), Patel; Mahesh V. (Salt Lake City, UT) |
|Assignee:|| Lipocine, Inc. (Salt Lake City, UT) |
Patent Claim Types:|
see list of patent claims
|Composition; Formulation; Dosage form; Delivery; Compound; Use; |
International Patent Family for Patent: 6,383,471
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