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Last Updated: February 4, 2023

Details for Patent: 6,383,471

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Summary for Patent: 6,383,471
Title: Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
Abstract:The present invention is directed to a pharmaceutical composition including a hydrophobic therapeutic agent having at least one ionizable functional group, and a carrier. The carrier includes an ionizing agent capable of ionizing the functional group, a surfactant, and optionally solubilizers, triglycerides, and neutralizing agents. The invention further relates to a method of preparing such compositions by providing a composition of an ionizable hydrophobic therapeutic agent, an ionizing agent, and a surfactant, and neutralizing a portion of the ionizing agent with a neutralizing agent. The compositions of the invention are particularly suitable for use in oral dosage forms.
Inventor(s): Chen; Feng-Jing (Salt Lake City, UT), Patel; Mahesh V. (Salt Lake City, UT)
Assignee: Lipocine, Inc. (Salt Lake City, UT)
Application Number:09/287,043
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 6,383,471
Patent Claim Types:
see list of patent claims
Composition; Formulation; Dosage form; Delivery; Compound; Use;

Drugs Protected by US Patent 6,383,471

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 6,383,471

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 3763700 See Plans and Pricing
Canada 2366702 See Plans and Pricing
European Patent Office 1165048 See Plans and Pricing
World Intellectual Property Organization (WIPO) 0059475 See Plans and Pricing
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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Serving leading biopharmaceutical companies globally:

Johnson and Johnson

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