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Last Updated: April 23, 2024

Details for Patent: 6,383,471

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Summary for Patent: 6,383,471

Title:	Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
Abstract:	The present invention is directed to a pharmaceutical composition including a hydrophobic therapeutic agent having at least one ionizable functional group, and a carrier. The carrier includes an ionizing agent capable of ionizing the functional group, a surfactant, and optionally solubilizers, triglycerides, and neutralizing agents. The invention further relates to a method of preparing such compositions by providing a composition of an ionizable hydrophobic therapeutic agent, an ionizing agent, and a surfactant, and neutralizing a portion of the ionizing agent with a neutralizing agent. The compositions of the invention are particularly suitable for use in oral dosage forms.
Inventor(s):	Chen; Feng-Jing (Salt Lake City, UT), Patel; Mahesh V. (Salt Lake City, UT)
Assignee:	Lipocine, Inc. (Salt Lake City, UT)
Application Number:	09/287,043
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 6,383,471
Patent Claim Types: see list of patent claims	Composition; Formulation; Dosage form; Delivery; Compound; Use;

Drugs Protected by US Patent 6,383,471

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent 6,383,471

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Australia	3763700	⤷ Try a Trial
Canada	2366702	⤷ Try a Trial
European Patent Office	1165048	⤷ Try a Trial
World Intellectual Property Organization (WIPO)	0059475	⤷ Try a Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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