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Last Updated: February 3, 2023

Details for Patent: 6,346,532


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Summary for Patent: 6,346,532
Title: Amide derivatives or salts thereof
Abstract:##STR1## Amide derivatives represented by general formula (I) or salts thereof wherein each symbol has the following meaning: ring B: an optionally substituted heteroaryl optionally fused with a benzene ring; X: a bond, lower alkylene or lower alkenylene optionally substituted by hydroxy or lower alkyl, carbonyl, or a group represented by --NH-- (when X is lower alkylene optionally substituted by lower alkyl which may be bonded to the hydrogen atom bonded to a constituent carbon atom of ring B to form lower alkylene to thereby form a ring); A: a lower alkylene or a group represented by -(lower alkylene)--O--; R.sup.1a and R.sup.1b : the same or different and each hydrogen or lower alkyl; R.sup.2 : hydrogen or halogeno; and Z: nitrogen or a group represented by .dbd.CH--. The compounds are useful as a diabetes remedy which not only functions to both accelerate the secretion of insulin and enhance insulin sensitivity but has an antiobestic action and an antihyperlipemic action based on its selective stimulative action on a .beta..sub.3 receptor.
Inventor(s): Maruyama; Tatsuya (Tsukuba, JP), Suzuki; Takayuki (Tsukuba, JP), Onda; Kenichi (Tsukuba, JP), Hayakawa; Masahiko (Tsukuba, JP), Moritomo; Hiroyuki (Tsukuba, JP), Kimizuka; Tetsuya (Tsukuba, JP), Matsui; Tetsuo (Tsukuba, JP)
Assignee: Yamanouchi Pharmaceutical Co., Ltd. (Tokyo, JP)
Application Number:09/529,096
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 6,346,532
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;

Drugs Protected by US Patent 6,346,532

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Apgdi MYRBETRIQ GRANULES mirabegron FOR SUSPENSION, EXTENDED RELEASE;ORAL 213801-001 Mar 25, 2021 RX Yes Yes See Plans and Pricing See Plans and Pricing Y See Plans and Pricing
Apgdi MYRBETRIQ mirabegron TABLET, EXTENDED RELEASE;ORAL 202611-001 Jun 28, 2012 AB RX Yes Yes See Plans and Pricing See Plans and Pricing Y See Plans and Pricing
Apgdi MYRBETRIQ mirabegron TABLET, EXTENDED RELEASE;ORAL 202611-002 Jun 28, 2012 AB RX Yes Yes See Plans and Pricing See Plans and Pricing Y See Plans and Pricing
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 6,346,532

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan9-285778Oct 17, 1997
PCT Information
PCT FiledOctober 15, 1998PCT Application Number:PCT/JP98/04671
PCT Publication Date:April 29, 1999PCT Publication Number: WO99/20607

International Family Members for US Patent 6,346,532

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 017340 See Plans and Pricing
Austria 266639 See Plans and Pricing
Australia 736676 See Plans and Pricing
Australia 8928898 See Plans and Pricing
Australia 9462198 See Plans and Pricing
Brazil 9804500 See Plans and Pricing
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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Serving leading biopharmaceutical companies globally:

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