|Title:||Method of providing sustained analgesia with buprenorphine|
|Abstract:||A method of effectively treating pain in humans is achieved by administering buprenorphinein accordance with first order kinetics over an initial three-day dosing interval, such that a maximum plasma concentration from about 20 pg/ml to about 1052 pg/ml is attained, and thereafter maintaining the administration of buprenorphine for at least an additional two-day dosing interval in accordance with substantially zero order kinetics, such that the patients experience analgesia throughout the at least two-day additional dosing interval.|
|Inventor(s):||Reder; Robert F. (Greenwich, CT), Kaiko; Robert F. (Weston, CT), Goldenheim; Paul D. (Wilton, CT)|
|Assignee:||Euro-Celtique S.A. (Luxembourg, LU)|
Patent Claim Types:|
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Back Citations: 26th percentile
Forward Citations: 1st percentile
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