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Details for Patent: 6,303,661

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Patent 6,303,661 protects KAZANO, JENTADUETO XR, OSENI, JUVISYNC, NESINA, GLYXAMBI, TRADJENTA, and JENTADUETO, and is included in eight NDAs. There have been zero Paragraph IV challenges on Tradjenta, Jentadueto, and Juvisync.

This patent has fifty-one patent family members in twenty-one countries.

Summary for Patent: 6,303,661

Title: Use of dipeptidyl peptidase IV effectors for lowering the blood glucose level in mammals
Abstract:Novel therapeutic regimens are provided which comprise the administration of therapeutically effective amounts of an inhibitor to dipeptidyl peptidase (DP-IV) or enzymes of similar activity whereby their ability to degrade the incretins, GLP-1 and GIP, is reduced. As a result hyperglycemia, such as that accompanying food intake may be reduced due to improved insulin release. A preferred therapeutic regimen amongst a number of routes of administration and inhibitors that may be used comprises the oral administration of isoleucyl thiazolidine.
Inventor(s): Demuth; Hans-Ulrich (Halle, DE), Rosche; Fred (Dieskau, DE), Schmidt; Joem (Halle, DE), Pauly; Robert P. (Vancouver, CA), McIntosh; Christopher H. S. (Vancouver, CA), Pederson; Ray A. (Vancouver, CA)
Assignee: Probiodrug (Weinbergweg, DE)
Application Number:09/155,833
Patent Claim Types:
see list of patent claims
Use; Dosage form; Composition;
Patent Metrics:
Source: PatentQuant.com
Field: Not categorized
Back Citations: 27th percentile
Forward Citations: 3rd percentile

Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Takeda Pharms Usa
KAZANO
alogliptin benzoate; metformin hydrochloride
TABLET;ORAL203414-002Jan 25, 2013RXYes6,303,661► subscribe METHODS OF LOWERING ELEVATED POST PRANDIAL BLOOD GLUCOSE LEVELS COMPRISING ADMINISTERING A DIPEPTIDYL PEPTIDASE INHIBITOR
Takeda Pharms Usa
KAZANO
alogliptin benzoate; metformin hydrochloride
TABLET;ORAL203414-001Jan 25, 2013RXNo6,303,661► subscribe METHODS OF LOWERING ELEVATED POST PRANDIAL BLOOD GLUCOSE LEVELS COMPRISING ADMINISTERING A DIPEPTIDYL PEPTIDASE INHIBITOR
Boehringer Ingelheim
JENTADUETO XR
linagliptin; metformin hydrochloride
TABLET, EXTENDED RELEASE;ORAL208026-001May 27, 2016RXNo6,303,661► subscribe METHOD OF TREATING TYPE 2 DIABETES MELLITUS BY ADMINISTERING A DIPEPTIDYL PEPTIDASE-IV INHIBITOR
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Foreign Priority and PCT Information for Patent: 6,303,661

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Germany196 16 486Apr 25, 1996
PCT Information
PCT FiledApril 24, 1997PCT Application Number:PCT/DE97/00820
PCT Publication Date:November 06, 1997PCT Publication Number: WO97/40832

International Patent Family for Patent: 6,303,661

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria202705► subscribe
Australia3023397► subscribe
Australia721477► subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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