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Last Updated: October 28, 2020

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Details for Patent: 6,248,358

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Summary for Patent: 6,248,358
Title: Bioadhesive progressive hydration tablets and methods of making and using the same
Abstract:A bioadhesive tablet wherein the active ingredient may be protected from water or the surrounding environment, thereby protecting it from metabolism or from other degradation caused by moisture, enzymes, or pH effects, and making it bioavailable only at a controlled rate. The active ingredient may be protected from moisture during the manufacturing process and more importantly may be protected from moisture and the immediate septic environment until after the patient has applied the tablet, and then only at a slow and controlled rate. It is by this process of progressive hydration that the active ingredient remains protected for many hours after administration. It is also by the process of progressive hydration that controlled and sustained release is achieved because only that part of the active ingredient that is the hydrated (aqueous) fraction of the tablet is available for absorption (bioavailable).
Inventor(s): Bologna; William J. (Paris, FR), Levine; Howard L. (Oceanside, NY), Cartier; Philippe (Paris, FR), de Ziegler; Dominique (Paris, FR)
Assignee: Columbia Laboratories, Inc. (Rockville Centre, NY)
Application Number:09/379,310
Patent Claim Types:
see list of patent claims
Dosage form; Delivery; Composition; Use; Process;

Drugs Protected by US Patent 6,248,358

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 6,248,358

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 016650   Start Trial
Argentina 032352   Start Trial
Argentina 036972   Start Trial
Argentina 043088   Start Trial
Austria 253892   Start Trial
Austria 306253   Start Trial
Australia 5582699   Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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Serving leading biopharmaceutical companies globally:

Harvard Business School
Express Scripts

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