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Last Updated: September 24, 2022

Details for Patent: 6,071,523


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Summary for Patent: 6,071,523
Title: Spill resistant pharmaceutical compositions in semi-solid form
Abstract:A spill-resistant pharmaceutical formulation for oral administration from a squeezable container comprises a pharmaceutical agent in a suitable vehicle comprising a liquid base and a thickening agent, the formulation consisting of mutually compatible components and having the following properties: a viscosity within the range of about 7500 to about 12,500 cps using a Brookfield Viscometer with a `C` spindle with Helipath movement at a spindle speed of 20 rpm and 20-25.degree. C., a viscometric yield value of a semi-solid, a spill-resistant consistency permitting the composition to be squeezed by light manual pressure through a channel, to spread in a spoon bowl sufficiently quickly for accurate measurement, and to remain in the spoon bowl without spilling on spoon inversion, tilting at 90 degrees, and vibration, homogeneity such that the components do not separate under conditions of use, and a storage stability such that the foregoing properties are retained for at least two years shelf life. A method for producing a formulation for a spill-resistant pharmaceutical composition comprises combining a per-unit dose effective amount of a pharmaceutical agent with suitable vehicle components comprising a liquid base and a thickening agent, and testing the formulation for acceptance criteria.
Inventor(s): Mehta; Rakesh (Nanuet, NY), Moros; Dan (Larchmont, NY)
Assignee: Taro Pharmaceuticals Industries, Ltd. (IL)
Application Number:09/089,360
Patent Claim Types:
see list of patent claims
Formulation; Dosage form; Composition; Delivery;

Drugs Protected by US Patent 6,071,523

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 6,071,523

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 312598 See Plans and Pricing
Austria 411796 See Plans and Pricing
Australia 2003271358 See Plans and Pricing
Australia 4326199 See Plans and Pricing
Australia 765798 See Plans and Pricing
Canada 2333405 See Plans and Pricing
Germany 69928927 See Plans and Pricing
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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Serving leading biopharmaceutical companies globally:

Dow
Baxter
Harvard Business School
AstraZeneca
Express Scripts
Medtronic

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