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Details for Patent: 6,011,020

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Patent 6,011,020 protects MACUGEN and is included in one NDA.

This patent has three hundred and sixty-five patent family members in thirty-six countries.

Summary for Patent: 6,011,020

Title: Nucleic acid ligand complexes
Abstract:This invention discloses a method for preparing a therapeutic or diagnostic complex comprised of a nucleic acid ligand and a lipophilic compound or non-immunogenic, high molecular weight compound by identifying a nucleic acid ligand by SELEX methodology and associating the nucleic acid ligand with a lipophilic compound or a non-immunogenic, high molecular weight compound. The invention further discloses complexes comprising one or more nucleic acid ligands in association with a lipophilic compound or non-immunogenic, high molecular weight compound.
Inventor(s): Gold; Larry (Boulder, CO), Schmidt; Paul G. (San Marino, CA), Janjic; Nebojsa (Boulder, CO)
Assignee: NeXstar Pharmaceuticals, Inc. (Boulder, CO)
Application Number:08/434,465
Patent Claim Types:
see list of patent claims
Compound; Use;

Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Valeant Pharms Llc
MACUGEN
pegaptanib sodium
INJECTABLE;INTRAVITREAL021756-001Dec 17, 2004RXYes6,011,020► subscribeY
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Non-Orange Book Patents for Patent: 6,011,020

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
6,566,343 High affinity nucleic acid ligands of complement system proteins► subscribe
5,766,853 Method for identification of high affinity nucleic acid ligands to selectins► subscribe
5,853,984 Use of nucleic acid ligands in flow cytometry► subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Because of the complexity of determining patent expiration dates it is advisable to have patent counsel verify freedom to operate.

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International Patent Family for Patent: 6,011,020

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria160821► subscribe
Austria256200► subscribe
Austria274520► subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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