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Last Updated: November 20, 2019

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Details for Patent: 5,998,581

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Summary for Patent: 5,998,581
Title: Reductive alkylation of glycopeptide antibiotics
Abstract:This invention is concerned with improved processes for reductive alkylation of glycopeptide antibiotics. The improvement residing in providing a source of copper which results in the initial production of a copper complex of the glycopeptide antibiotic. Reductive alkylation of this complex favors regioselective alkylation and increased yields. Copper complexes of the glycopeptide antibiotic starting materials and of the alkylated products are also part of the invention.
Inventor(s): Berglund; Richard Alan (Lafayette, IN), Lockwood; Nancy Anne (Mountlake Terrace, WA), Magadanz; Howard Eugene (Lafayette, ID), Zheng; Hua (Lafayette, ID)
Assignee: Eli Lilly and Company (Indianapolis, IN)
Application Number:09/290,204
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 5,998,581

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 5,998,581

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 010621   Start Trial
Austria 286910   Start Trial
Australia 5449798   Start Trial
Australia 723941   Start Trial
Brazil 9713523   Start Trial
Canada 2272240   Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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