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Generated: November 19, 2017

DrugPatentWatch Database Preview

Details for Patent: 5,994,409

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Which drugs does patent 5,994,409 protect, and when does it expire?


Patent 5,994,409 protects ETHYOL and is included in one NDA. There has been one Paragraph IV challenge on Ethyol.

This patent has fourteen patent family members in twelve countries.

Summary for Patent: 5,994,409

Title: Methods for treatment of neuro--and nephro--disorders and therapeutic toxicities using aminothiol compounds
Abstract:The present invention relates to new uses of S-2-(3-aminopropylamino)ethyl dihydrogen phosphorothioate, (amifostine) and other aminothiol compounds to treat and reverse toxicities caused by therapeutic agents, radiation treatment or diabetes. In particular, the invention provides a method for treating neurotoxicity and nephrotoxicity associated with the administration of chemotherapeutic agents.
Inventor(s): Stogniew; Martin (Blue Bell, PA), Alberts; David S. (Tucson, AZ), Kaplan; Edward H. (Skokie, IL)
Assignee: U.S. Bioscience, Inc. (West Conshohocken, PA) The Arizona Board of Regents on behalf of the University of Arizona (Tuscon, AZ)
Application Number:08/987,550
Patent Claim Types:
see list of patent claims
Use; Delivery;

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Clinigen Hlthcare
ETHYOL
amifostine
INJECTABLE;INJECTION020221-002Sep 10, 1999DISCNNoNo► Subscribe► Subscribe METHODS FOR USING THE DRUG PRODUCT
Clinigen Hlthcare
ETHYOL
amifostine
INJECTABLE;INJECTION020221-001Dec 8, 1995APRXYesYes► Subscribe► Subscribe METHODS FOR USING THE DRUG PRODUCT
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Non-Orange Book Patents for Patent: 5,994,409

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
6,586,476 Methods for the treatment of nephro-disorders using aminothiol compounds► Subscribe
7,105,575Methods for the treatment of neuro- disorders using aminothiol compounds► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Because of the complexity of determining patent expiration dates it is advisable to have patent counsel verify freedom to operate.

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International Patent Family for Patent: 5,994,409

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Portugal1039887► Subscribe
Japan2006188532► Subscribe
Japan2001525359► Subscribe
Spain2260857► Subscribe
European Patent Office1537861► Subscribe
European Patent Office1039887► Subscribe
Denmark1039887► Subscribe
Germany69834658► Subscribe
China1161113► Subscribe
China1283994► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Dow
Teva
Queensland Health
Johnson and Johnson
Argus Health
Deloitte
Express Scripts
McKesson
Mallinckrodt
McKinsey

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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